Early Signs Your Kidneys Are Failing — Know Symptoms

Dale Probst M.D.
6 min readMar 31, 2024

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According to the National Kidney Foundation, more than 37 million American adults have kidney disease, but most are unaware of it. Symptoms of kidney disease are often attributed to other conditions, and many people only experience symptoms in the late stages when the kidneys are failing. It is crucial for those at risk, such as individuals with high blood pressure, diabetes, a family history of kidney failure, or who are older than 60, to get tested annually for kidney disease. Dr. Joseph Vassalotti, Chief Medical Officer at the National Kidney Foundation, shares 10 possible signs of kidney disease, including fatigue, trouble sleeping, dry and itchy skin, increased frequency of urination, blood in the urine, foamy urine, puffiness around the eyes, swelling in the ankles and feet, poor appetite, and muscle cramps.

Signs Your Kidneys Are Failing

Feeling Fatigued and Having Trouble Concentrating

One of the early signs of kidney disease is feeling tired, having less energy, or experiencing difficulty concentrating. This can be caused by a severe decrease in kidney function, leading to a buildup of toxins and impurities in the blood. Anemia, which is common in kidney disease, can also contribute to weakness and fatigue.

When the kidneys fail to effectively filter waste products from the blood, toxins accumulate and can affect various organs, including the brain. As a result, individuals may feel mentally foggy, have trouble staying focused, and struggle with memory problems. This cognitive impact can significantly impact daily life and overall quality of life.

In addition to feeling fatigued and experiencing difficulties concentrating, other symptoms of kidney disease include changes in urine frequency and appearance, skin issues, and swollen ankles and feet. If you are experiencing any of these symptoms, it’s important to consult a healthcare professional for an accurate diagnosis and appropriate treatment.

  • Feeling tired and having low energy
  • Difficulty concentrating and mental fog
  • Memory problems
  • Changes in urine frequency and appearance
  • Dry and itchy skin
  • Puffiness around the eyes
  • Swelling in the ankles and feet
  • Poor appetite
  • Muscle cramps

Sleep Troubles

When the kidneys aren’t filtering properly, toxins remain in the blood instead of being eliminated through urine. This can make it difficult to sleep. Additionally, there is a link between obesity and chronic kidney disease, and sleep apnea is more common in individuals with kidney disease.

One of the early signs of kidney failure is sleep troubles, as the kidneys play a crucial role in regulating various bodily functions, including sleep. When the kidneys fail to filter waste and toxins effectively, it can lead to an imbalance of chemicals and hormones in the body. This imbalance can disrupt the natural sleep-wake cycle, making it difficult to fall asleep or stay asleep throughout the night.

Moreover, obesity is a significant risk factor for chronic kidney disease (CKD). Obesity increases the workload on the kidneys and can contribute to kidney damage over time. In individuals with kidney disease, sleep apnea, a condition characterized by interrupted breathing during sleep, is more prevalent. Sleep apnea can further disrupt sleep patterns and worsen the symptoms of kidney disease.

If you are experiencing sleep troubles or suspect kidney disease, it is essential to consult a healthcare professional. They can evaluate your symptoms, conduct diagnostic tests, and provide appropriate treatment strategies. Early detection and management of kidney disease can help improve sleep quality and overall kidney function.

It’s good to remember that sleep disturbances can have multiple causes, and kidney disease may not be the sole reason. However, if you notice sleep troubles along with other signs of failing kidneys or early signs of kidney failure, it is crucial to seek medical advice for a comprehensive evaluation.

Symptoms of Kidney Disease-Related Sleep Troubles:

  • Insomnia or difficulty falling asleep
  • Frequent waking up during the night
  • Restless legs syndrome (RLS)
  • Nighttime muscle cramps
  • Excessive daytime sleepiness
  • Snoring or sleep apnea

Tips for Managing Sleep Troubles in Kidney Disease:

  1. Practice good sleep hygiene: Establish a consistent sleep routine, create a calm sleep environment, and avoid stimulating activities before bedtime.
  2. Exercise regularly: Engage in regular physical activity, but avoid intense workouts close to bedtime.
  3. Manage stress: Find relaxation techniques that work for you, such as meditation or deep breathing exercises, to reduce stress and promote better sleep.
  4. Talk to your healthcare provider: Discuss your sleep troubles with your healthcare provider, as they may recommend lifestyle changes or refer you to a sleep specialist for further evaluation.

Skin Issues

Dry and itchy skin can be early indicators of kidney damage and mineral imbalances that often accompany advanced kidney disease. When the kidneys are no longer functioning properly, they are unable to maintain the proper balance of minerals and nutrients in the blood, leading to various skin problems.

Persistent dryness and itchiness can result from the buildup of waste products and toxins in the bloodstream, which the kidneys would normally filter out. Minerals like calcium and phosphorus can also accumulate in the body when kidney function declines, leading to conditions such as hyperphosphatemia and hypocalcemia, which can manifest as skin issues.

Furthermore, impaired kidney function can cause abnormalities in the body’s hormone production, leading to dry and rough skin. The reduced production of erythropoietin, a hormone that stimulates the production of red blood cells, can contribute to dryness and dullness.

Signs Your Kidneys Are Failing

Common Skin Issues Associated with Kidney Damage:

  • Severe dryness
  • Itchiness
  • Rash or skin irritation
  • Darkened or discolored patches
  • Excessive sweating
  • Fragile skin that bruises easily

If you notice persistent skin problems that are not responsive to over-the-counter treatments, it is vital to consult with a healthcare professional. These symptoms may indicate the presence of underlying kidney disease or other related complications.

Changes in Urination

One of the signs that your kidneys may be failing is a noticeable change in urination patterns. An increase in the frequency of urination, particularly at night, can be an indication of kidney disease. When the kidneys are damaged and unable to function properly, they may filter and produce more urine than usual, leading to the urge to urinate more frequently.

However, it’s important to note that increased urination can also be a symptom of other conditions, such as urinary infection or an enlarged prostate in men. Therefore, it is crucial to consult with a healthcare professional to determine the underlying cause of the urinary changes.

Urine Abnormalities

Kidney disease can manifest in various ways, including abnormalities in urine composition. These urine abnormalities can serve as important indicators of kidney health and potential kidney disease. It is crucial to be aware of the signs and symptoms that may suggest kidney dysfunction.

One notable urine abnormality is the presence of blood cells in the urine, which leads to the appearance of blood in the urine. This condition, known as hematuria, can be an indication of kidney disease. Hematuria can range from microscopic traces of blood, only detectable through laboratory tests, to visible red or brown discoloration of the urine. Therefore, anyone experiencing this symptom should consult a healthcare professional for further evaluation.

In addition to blood in the urine, another urine abnormality that may suggest kidney disease is the presence of foamy urine. Foamy urine resembles the foam observed when scrambling eggs. This frothy appearance can be caused by excess protein in the urine, a condition known as proteinuria. While a small amount of protein in the urine is normal, higher levels could be indicative of kidney problems. It is essential to consult a medical professional if foamy urine persists or if it is accompanied by other kidney disease symptoms.

It is important to note that urine abnormalities can be attributed to conditions other than kidney disease, such as tumors, kidney stones, or infections. Therefore, a thorough evaluation by a healthcare provider is necessary to determine the underlying cause.

How to Recognize Urine Abnormalities:

  • Visible blood in the urine
  • Dark or discolored urine
  • Foamy or frothy appearance of urine
  • Increased urgency or frequency of urination
  • Persistent changes in urine color or consistency

If you notice any of these urine abnormalities, it is essential to schedule an appointment with your healthcare provider to undergo further evaluation. Early detection of kidney disease can significantly improve treatment outcomes and help protect your overall kidney health.

Conclusion

Recognizing the early signs of kidney disease is crucial for early detection and treatment. It’s essential for individuals at risk to get tested regularly and report any symptoms to their healthcare provider.

Common signs of kidney disease include fatigue, sleep troubles, skin issues, changes in urination, urine abnormalities, puffiness around the eyes, swelling in the ankles and feet, poor appetite, and muscle cramps.

If you suspect kidney disease, consult a medical professional for diagnosis and appropriate treatment. Early intervention can help protect your kidney health and overall well-being.

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