CONCLUSIONS: This cohort study confirms the need for continuous, structured and multidisciplinary lifelong monitoring of TS, thus ensuring the early diagnosis of important comorbid conditions, including cancer, and their appropriate and timely treatment. In addition, these data highlight the need for the increased surveillance of specific types of cancer in TS, including thyroid carcinoma. https://pubmed.ncbi.nlm.nih.gov/35907176/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1HaIafHQm-6ixXDuOGQDZK3BTBlRSE5zc5tHU8zzzboDtqXsyi&fc=20220702142008&ff=20220730195427&v=2.17.7
Elevated cardiac troponin I and short-term mortality in patients with acute type A aortic dissection
CONCLUSION: Elevated cTnI is common in patients with ATAAD, and is associated with increased 30-day mortality risk. https://pubmed.ncbi.nlm.nih.gov/35905196/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1HaIafHQm-6ixXDuOGQDZK3BTBlRSE5zc5tHU8zzzboDtqXsyi&fc=20220702142008&ff=20220729190713&v=2.17.7
CONCLUSION: Obesity, interacting with age, increases the risk of in-hospital mortality in patients with AAD undergoing open surgical repair. Although more verification is needed, we believe these findings provide further evidence for the treatment of AAD. https://pubmed.ncbi.nlm.nih.gov/35903673/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1HaIafHQm-6ixXDuOGQDZK3BTBlRSE5zc5tHU8zzzboDtqXsyi&fc=20220702142008&ff=20220729065905&v=2.17.7
CONCLUSIONS: We detected distinct genetic loci underpinning the diameters of the LVOT, aortic root, and at several segments of ascending aorta. We spatially defined a region of aorta whose genetics may be most relevant to predicting thoracic aortic aneurysm. We further described a genetic signature that may predispose to aortic stenosis. Understanding genetic contributions to proximal aortic diameter may enable identification of individuals at risk for aortic disease and facilitate… https://pubmed.ncbi.nlm.nih.gov/35902171/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1HaIafHQm-6ixXDuOGQDZK3BTBlRSE5zc5tHU8zzzboDtqXsyi&fc=20220702142008&ff=20220729010139&v=2.17.7
The Pediatric Heart Network (PHN) trial showed similar efficacy of β-blockers (BB) and angiotensin receptor blockers (ARB) for aortic root dilation in Marfan syndrome, but the impact on prescription practices is unknown. We hypothesized BB and ARB prescriptions would increase after the trial results were published (2014). Prescription data (2007–2016) were obtained from outpatient encounters (IBM Marketscan) for Marfan syndrome patients (6 months-25 years old). Excluding 2014 as a washout… https://pubmed.ncbi.nlm.nih.gov/35902413/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1HaIafHQm-6ixXDuOGQDZK3BTBlRSE5zc5tHU8zzzboDtqXsyi&fc=20220702142008&ff=20220729010139&v=2.17.7
BACKGROUND Acute aortic syndrome (AAS) is a spectrum of severe life-threatening disease processes that are often initially encountered in the emergency department (ED) setting and require prompt recognition and treatment to prevent significant complications, including death. We describe an atypical presentation of aortic intramural hematoma in a female patient during sexual intercourse, a situation not previously described in the literature. CASE REPORT The patient was a 45-year-old woman who… https://pubmed.ncbi.nlm.nih.gov/35898118/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1HaIafHQm-6ixXDuOGQDZK3BTBlRSE5zc5tHU8zzzboDtqXsyi&fc=20220702142008&ff=20220728071618&v=2.17.7
CONCLUSION: Massive bleeding in ATAAD patients who underwent emergent aortic repair is highly associated with gender, emergent surgery, increased D-dimer levels, longer CPB time, anemia, and use of a complex surgical strategy. Since massive bleeding may lead to worse outcomes, surgeons should choose suitable surgical strategies in patients who are at a high risk of massive bleeding. https://pubmed.ncbi.nlm.nih.gov/35898275/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1HaIafHQm-6ixXDuOGQDZK3BTBlRSE5zc5tHU8zzzboDtqXsyi&fc=20220702142008&ff=20220728071618&v=2.17.7
