Published inPacBioDecoding A Coastal Giant: Full-Length Transcriptome of Sequoia sempervirensAncient Giants of The LandJan 18, 2021Jan 18, 2021
Published inPacBioA Genome Fit for a Giant — Sequencing the California RedwoodThis is a guest post by Michelle Vierra (@the_mvierra)Mar 4, 2020Mar 4, 2020
Published inPacBioHiFi Assembler Series, Part 2: HiCanu, near optimal repeat resolution using HiFi readsNOTE 1: This is a four-part series on genome assemblers using PacBio HiFi reads. Read part 1 on hifiasm here.Feb 20, 20201Feb 20, 20201
Published inPacBioHiFi Assembler Series, Part 1: hifiasm, a fast, haplotype-resolved genome assemblerNOTE 1: This is a four-part series on genome assemblers using PacBio HiFi reads.Feb 12, 2020Feb 12, 2020
Published inPacBioHidden in Plain Sight — A Bioinformatics Journey into Structural Variation Calling in the Long…I first met Fritz Sedlazeck (@sedlazeck) in 2015 at the American Society of Human Genetics (ASHG) meeting. It was at a bar in Baltimore…Jan 21, 20201Jan 21, 20201
Published inPacBioYour Drug Mileage May Vary: The PIK3CA Double Mutation Story“People have studied the PIK3CA gene for 20 years, yet no one has looked into how double mutations of the gene affects drug response in…Dec 18, 2019Dec 18, 2019
Published inPacBioFinding Diagnosis in a Sea of Transcripts: The Case of a Hypertrophic Cardiomyopathy PatientMost of the time, genetic diagnosis is about the genome, not the transcriptome. Since many of the genetic causes for diseases are already…Sep 24, 2019Sep 24, 2019
Published inPacBioA Tale of Mutants: Sequencing the Full-Length Influenza Virus at the Single Cell LevelIt was February 2019 in Seattle. Outside the Fred Hutchinson Cancer Research Center, it was snowing — a rare event for the temperate…Jun 17, 2019Jun 17, 2019
Published inPacBioSMRT Leiden 2019 Day 3: Bioinformatics for Transcriptome, Genome Analysis, and Targeted SequencingGene Myers (@TheGeneMyers, MPI-CBG, Germany) delivered the keynote for the last day of SMRT Leiden 2019, which is dedicated to…May 9, 2019May 9, 2019
Published inPacBioSMRT Leiden 2019 Day 2: Evolving Towards Precision Medicine with Longer, Accurate Reads“I want the country that eliminated polio and mapped the human genome to lead a new era of medicine — one that delivers the right…May 8, 2019May 8, 2019
