

Cryptocurrency Investor. Tech Junkie. World Traveler. Crohn's Disease Fighter & Chronic Illness Advocate.
The current prevailing theory is that persistent immune activation is what causes fatigue in people with Crohn’s disease and other inflammatory diseases like lupus and ankylosing spondylitis. In healthy people, the immune system is generally pretty chilled out and activates only when it identifies a threat. In people with autoimmune diseases, however, the immune system is in an “always-on” mode, always perceiving a threat (usually the person’s own body). This constant alertness requires a large amount of energy resources.