Norman Spack, MD, reported, in passing, about a trans youth who was diagnosed as bipolar and after going on blockers the bipolar symptoms vanished. The shrink quipped to Spack that the bipolarity likely was cause by having to live in two genders. Once the real gender was affirmed, things righted. I have seen this too in other cases of trans people.
And yes, all people have life problems, but getting rid of this is so important. “I did not know how heavy a load I carried until I get it down.”