Why is _able Partners, a consumer fund, investing in pharma companies developing illegal drugs? We believe these stigmatized substances, psychedelics, can help address “The Wellness Gap” — the disconnect between accelerating economic indicators (GDP per capita) and declining measures of physical and emotional wellbeing.

One of our portfolio companies, COMPASS Pathways, is using the active ingredient in magic mushrooms, psilocybin, to develop a new model for drug-assisted psychotherapy. In 2018 the FDA granted COMPASS ‘breakthrough therapy’ designation (meaning the treatment demonstrated such potential that the development and review process are expedited) for research into psilocybin for treatment-resistant depression. …


Millions of women — and investors alike — can benefit from real innovation

Every day an estimated 6,000 women in the U.S. enter menopause (or 2 million a year), a natural part of the aging process during which a woman’s body experiences significant changes in two critical hormones, estrogen and progesterone. In addition to side effects including hot flashes, mood changes, insomnia and vaginal dryness, the rapid decrease in estrogen may also increase the risk of other health conditions including osteoporosis and heart disease. At least 20% of the U.S. workforce is currently in menopause and four out of five women will experience symptoms.¹ For relative scale, approximately 2 million women get married each year. However, unlike the wedding industry, there are far fewer products, services and resources designed to support aging women. In many ways, we have signaled to women that they are no longer a priority as their years of fertility have ended. …


_able Partners shares their thoughts on 2020

The 2010’s gave us the iPad, Instagram, Slack, Fitbits, gluten-free foods, and thousands of CBD products, all optimistically designed to make our lives healthier and more connected. But increasingly, we see that these well-intended innovations may have contributed to an opposite outcome. We are entering a new decade with a monkey on our nation’s back: “The Wellness Gap” — the term we use to describe the disconnect between economic growth and measures of wellbeing. While GDP per capita continues to climb, recent data shows that physical and mental health have plummeted.

U.S. life expectancy has fallen over the last three years,¹ representing the longest consecutive decline since World War I. Some Americans are expected to live shorter lives than their parents, and much of it is due to behavioral health issues including depression and addiction often resulting in accidental deaths. Millennials, often glorified for their impact and influence, now carry the infamy of a skyrocketing mortality rate: without intervention, they could be 40% more likely to die compared to the previous generation at a comparable age.² …

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