Linkage Disequilibrium

Howard Wetsman MD
Nov 3 · 3 min read

A gene may have many places where there are Single Nucleotide Polymorphisms (SNPs), and these can generally be reshuffled in every generation by a process called recombination, which I wrote about here. In a perfectly random world, the association between all these SNPs will be random in any given population. However, the world is not perfectly random.

It turns out that some SNPs travel together through time and generations. Such SNPs are said to be in linkage disequilibrium. Perhaps they are so close that they almost always get recombined together. Perhaps they are both on a part of the…

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Howard Wetsman MD

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Addictionologist educating the world soon at GenEdSystems.com. Solves problems with TOC. Author of Questions and Answers on Addiction. Twitter: @addictiondocMD

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