Nerve Tests for ALS

Als Deanna
3 min readDec 6, 2021

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When a person is suspected to have a condition like the ALS or amyotrophic lateral sclerosis, it’s typically only verified after a battery of testing has been completed to establish an accurate diagnosis. There’s no one, definitive diagnostic instrument, therefore it’s typically a case of banned alternative possibilities before coming to a definite judgment.

This is due to the fact that numerous illnesses have symptoms with ALS. A symptom like not being able to handle a pen or a cup correctly, for example, might indicate carpal tunnel syndrome or something more serious like multiple sclerosis (MS). Nerve testing is one aspect of the ALS diagnosis procedure that is often performed.

What are Nerve Tests and How Do They Work?

Because ALS affects the nerves directly, the patient may be requested to engage in electrophysiological testing if the condition is suspected. After all, other options have been ruled out, these tests look at how the muscles and nerves are working to see whether they are equivalent to an ALS diagnosis. They are insufficient on their own since muscle and nerve dysfunction can emerge as a result of other health problems such as a spinal cord injury, MS, or Parkinson’s Diseases. In order to diagnose ALS, two nerves and muscle tests are routinely employed. Electromyography (EMG) and nerve conduction velocity studies are the terms of these tests (NCS).

Electromyography (EMG)

When a patient is asked to flex their leg, electromyography measures the response of a muscle or group of muscles. On an oscilloscope, data concerning the engagement of little needles in the muscle are captured. The test normally takes 15–30 minutes, depending on the patient’s health. This device displays muscle electrical activity in waves. The muscle is tested in three states: relaxed, slightly contracted, and fully contracted. After the electrodes are attached, the patient may be asked to lift or flex an arm or leg depending on the area being assessed. Since no nerve impulses are being sent, the muscles should be completely silent. A purposeful arm or leg movement creates a signal. The wave’s size indicates how successfully the nerve impulses work. Less vigorous contractions should increase the wave size. In ALS, the test should show a reduce wave, suggesting that nerve transmission is less than normal. However, this alone is not enough to diagnose the illness.

Nerve Conduction Experiment (NCS)

Like an EMG, an NCS measures the speed of nerve transmission. This is called a nerve conduction test (NCT). It operates by delivering a nerve impulse from one part of the body to another and measuring its speed. This involves attaching an electrode to one part of the body and another electrode ‘downstream. ‘ During the test, the patient may feel a little shock or tingling when an impulse travels from the top electrode to the bottom electrode. The idea is to determine how fast an impulse travels through the body. If the person has nerve damage, they will generally see a prolonged transmission period. Preparation for these nerve tests is minimal. If needles are used, there may be some discomfort, but both procedures are rather painless and should take no more than 30 minutes. These tests can be used to diagnose ALS, but they can also be used to monitor disease progression, such as assessing the patient’s muscle weakness. These tests cannot diagnose ALS as it owned and if someone has ALS, they should expect to show signs of nerve damage.

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