Join TrialMatch and be the cure

Alzheimer’s Association TrialMatch is a clinical studies matching service that connects individuals with current studies.

Alzheimer’s disease is reaching epidemic proportions. The immediate need for advances in prevention and treatment methods has led to an unprecedented call for clinical trial participants. Before any drug or therapy can be used in clinical practice, it must be rigorously tested to find out whether it is safe and effective in humans.

“Since its debut in 2010, Alzheimer’s Association TrialMatch has connected more than 87,000 people with comprehensive clinical trial information and a customized list of studies they may seek to enroll in,” said Catherine James, chief executive officer for the Alzheimer’s Association, Central New York Chapter. “TrialMatch is open to people with Alzheimer’s disease or related dementias, their caregivers, family members and physicians.”

Using this Web-based service (, TrialMatch users create and manage a personal profile that includes information about their diagnosis, location and other preferences. This profile is then matched with a continuously updated database of Alzheimer’s disease and dementia clinical trials. New users receive a customized list of potential study matches and can choose to be notified via email when a new study that matches their profile is added to the database.

For people with Alzheimer’s and their caregivers, participating in research studies presents an opportunity to play a more active role in their own treatment, contribute to research that could change the course of the disease, and benefit future generations.

“Recruiting and retaining trial participants is now the greatest obstacle, other than funding, to developing desperately needed treatments for Alzheimer’s disease,” said James. “With TrialMatch, we can fill trials faster, which can help us get answers faster and bring us closer to finding better treatments for Alzheimer’s.”

People in clinical trials may gain access to potential treatments before they are widely available. They may also receive expert medical care at leading health care facilities, often free of cost.

More than 5 million Americans are living with Alzheimer’s disease, according to the Alzheimer’s Association 2017 Alzheimer’s Disease Facts and Figures report. By 2050, the number of people with Alzheimer’s may nearly triple, to as many as 13 million, barring the development of medical breakthroughs to prevent, slow or stop the disease.

Alzheimer’s Association TrialMatch is easy to use — with web and phone support, specially trained staff and tools developed with input from people with Alzheimer’s — and is available to users free of cost. As of December 2015, more than 150,000 individuals have registered to search for Alzheimer’s clinical trials. Currently, TrialMatch lists more than 250 research studies at over 700 local trial sites across the United States and Canada. These include treatment, prevention, diagnostic, and quality-of-life studies.

The strength of this service is its comprehensive, constantly updated database of Alzheimer’s, mild cognitive impairment and other dementia trials. Patients and caregivers are encouraged to share their trial matches with their health care professionals to help decide whether a clinical trial is appropriate.

How to use Alzheimer’s Association TrialMatch

STEP 1: Access TrialMatch online at or by calling (800) 272–3900.

STEP 2: Complete a brief questionnaire, either online or over the phone, to create a profile.

STEP 3: Based on specified eligibility criteria (i.e., diagnosis, treatment history, location), the Alzheimer’s Association will provide a customized list of potential matches to identify studies you would like to pursue.

STEP 4: Contact the site coordinator listed for the study or studies of interest to you to determine next steps. Alzheimer’s Association TrialMatch specialists are available from 8 a.m. to 8 p.m. CT, Monday through Friday to answer questions about the TrialMatch service.