The Effects of Sugar-based Excipients on The Attributes of Novel Generic Ketoconazole Tablet Formulations, as Well as Stability Testing with the Direct Compression Technique
Excipients are inactive ingredients used to support the active ingredient of the treatment, as well as to bulk up the solid formulation and offer long-term stability. Excipients come in a variety of forms and types, including gum, syrups, starch, and others. This also reduces the viscosity of the entire drug and improves its solubility.
Excipients provide medicine flavor and cover it with different colors so that it looks different and has varied textures. Immaculate sugar and polymer, complex starches, and even human and gelatin are used as excipients. The pharmaceutical industry has mostly adopted sugar-based excipients because they are simple to use and can be simply coated over tablets. As a hindrance to the ability of Sugar-based Excipients that have received regulatory approval.
The most frequent type of excipient used in oral medication is a sugar-based excipient. It is particularly important for drugs intended for youngsters. It’s found in a variety of products, including sucrose, glycerol, saccharin sodium, sorbitol, and others. Antibiotics and cough syrups for youngsters are the most common examples.
Sugar-based Excipients have gained widespread acceptance as pharmaceutical tableting components. They can be used to disguise the bitterness of active ingredients, making them more palatable. The demand for compressible sugar-based excipients has increased since direct compression has become the predominant method of tablet manufacturing.
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