Axial — Observations #6

Axial
5 min readApr 17, 2020

Get these analyses to your inbox — https://axialobservations.substack.com/ This is a newsletter for rough-around-the-edges ideas. More well thought out work can be found at — https://axial.substack.com/ I figured that there is a diversity across desire for frequency of emails.

Axial invests and partners in early-stage life sciences companies. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company — info@axialsprawl.com

A set of ideas and observations from a week’s worth of work analyzing businesses and technologies.

Diagnostics and IP

How strong of technical moats do diagnostic companies really have? Two court cases, Mayo v. Prometheus Laboratories (2012, Supreme Court) — https://en.wikipedia.org/wiki/Mayo_Collaborative_Services_v._Prometheus_Laboratories,_Inc. and Vanda Pharmaceuticals v. Ward Pharmaceuticals (2018 Federal Appeals Court) — https://www.patentdocs.org/2018/07/uspto-issues-memorandum-on-vanda-pharmaceuticals-v-west-ward-pharmaceuticals.html are two major legal decisions that influence that moat.

In 2012, the US Supreme Court ruled that optimizing the dose of a drug based on the metabolites of that drug were being directed by a law of nature and were patent-ineligible. In 2018, the US Court of Appeals for the Federal Circuit ruled in a case where the dose of a drug (iloperidone for schizophrenia in the case) was determined by the patient’s genotype…

--

--