Ben LiesfeldinLimbus News“The varvis® Software: The first genomics end-to-end software certified as IVDR Class C device”Genetic diagnostic laboratories now have access to the first complete genomics software solution which is certified as a Class C device…May 31May 31
Ben LiesfeldinLimbus NewsQ&A: The role of the IVDR conformity assessment in genetic diagnosticsNow that the regulation on in-vitro diagnostic devices (IVDR) explicitly regulates in-house devices, or laboratory-developed tests (LDTs)…May 31May 31
Ben LiesfeldinLimbus NewsThe AWS S3 Denial of Wallet Amplification AttackIf you publicly host large data files on AWS S3 & pay for transfer costs, you may be vulnerable to a “Denial of Wallet” amplification…May 22May 22
Ben LiesfeldinLimbus NewsAn MDCG guideline for laboratory developed tests under IVDRThere have been a lot of discussions about what IVDR Art 5(5) means for genetic diagnostic labs. In January 2023, the Medical Device…Jan 25, 2023Jan 25, 2023
Ben LiesfeldinLimbus NewsKnown issues with genome build hg38Back in 2020 we were advertising hg38 as the better reference genome and highlighted potential challenges when transitioning from hg19 to…Aug 19, 2022Aug 19, 2022
Ben LiesfeldinLimbus NewsCan you determine the specificity of an NGS assay?We have seen this many times: scientists calculate sensitivity and specificity of their NGS assay. These are the standard performance…Sep 7, 2021Sep 7, 2021
Ben LiesfeldinLimbus NewsLimbus, University of Rostock win grant to apply AI to variant interpretationThe Modeling and Simulation Group at the University of Rostock joins forces with Limbus Medical Technologies GmbH in the 1.5 mEUR research…Nov 17, 2020Nov 17, 2020
Ben LiesfeldinLimbus NewsRefSeq Select — a standardized algorithm to select your preferred RefSeq transcriptWhich transcript should I use to report a genomic variant? This is a frequent question from clinical geneticists now that Whole Exome…Oct 2, 2020Oct 2, 2020
Ben LiesfeldinLimbus NewsHigh-sensitivity solutions for liquid biopsy from NGSThe varvis® software supports various technologies that allow to use NGS for tumor diagnostics or liquid biopsy applications.Aug 14, 2020Aug 14, 2020
Ben LiesfeldinLimbus NewsThe human reference genome hg38 in clinical diagnosticshg38 is the old new standard for genomics. It has been almost 6 years since the official release of hg38 in 2013. Even though it provides…Jun 10, 2020Jun 10, 2020