Bad eating habits will be inherited by offspring
In recent years, more and more evidence suggests that certain acquired traits can be passed on to the next generation. However, the inheritance of acquired traits still remains controversial because people don’t know the exact molecular mechanisms behind this phenomenon. Epigenetic modifications can regulate gene expression without altering the DNA sequence of the case. On March 14, a study published in the journal Nature Genetics confirms parents’ behavior influence a child’s health through epigenetics. Scientists have found that although poor diet isn’t introduced to mutations, its health effects can continue into the next generation through the egg and sperm.
German scientist and his colleagues Peter Huypens same genetic background mice were divided into three groups, in the six weeks to provide them with high-fat, low-fat diet and normal, respectively. High-fat diet mice getting fatter, and exhibit glucose intolerance (an early manifestation of Type II diabetes).
The researchers collected the eggs and sperm of mice in vitro fertilization (IVF), IVF and embryo transfer to maternal health in vivo. In this way they exclude a variety of confounding factors including microbial group including, IVF mice exhibit the trait or behavior can only come from the egg and sperm.
Researchers in adult mice after IVF to provide high-fat diet. They found that parents are more likely to fat mice weight gain and glucose intolerance, parents have lost the least weight gain in mice. That is, the adverse health effects of diet parents can be superimposed.
This study shows that there is a gender difference between IVF mice. In the case of obese parents, female mice were more likely to gain weight IVF, IVF and male mice easier glucose intolerant. In addition, compared with his father’s eating habits, eating habits of the mother’s children a greater metabolism. Previous studies have also found a human pandemic similar phenomenon.
So, exactly how these traits passed down it? Currently epigenetic mechanisms have been proposed mainly two: DNA methylation and microRNA. The researchers found that obese mice and healthy mice methylation patterns and RNA transcripts differences do exist, but it is unclear whether the reasons for these differences are that IVF offspring affected.
In the nature, all parents can own DNA for future generations. However, parental influence on children is far more than that. Such as epigenetic, pregnancy and childbirth, breastfeeding and parenting process. It is these gifts go beyond genes that children can grow up to be healthy to deal with the challenges of this world. Prior to the launch of The journal Science released special issues of parenting to the people through a series of articles, pointing out that raising children is not only providing children with food, shelter, protection and education. Generalized child care in the broad sense actually starts before ingravidation.