Americans are rightfully very leery of trade deals after they were told by both parties that NAFTA was a good thing. The unions no longer have the clout/votes to look after the worker. There will be future trade deals where the American workers jobs will be seen as a priority.
In reality TPP or any international trade agreement is more complex than I and expect you understand.
I hope in future a non partisan worker impact statement will be made available to the public on any future agreements.