I can totally see going to hyperscript for react native. Let’s be honest, react native is dom-like in appearance only and has no relation to web browser DOM.
For react web however, I actually have gone a bit the other way, and use a hybrid approach staring with: https://github.com/wix/react-templates
I use the JSX approach for my mid-tier components which themselves usually have a small chunk of html attached, but are more behavior than anything else.
I often end up with something like this: