Researchers at UC San Diego created the largest maps of gene regulation to date, capturing the network of RNA binding proteins, the RNA sequences they bind to, and what the proteins do.

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Can you imagine organizing more than 10 terabytes of data into a useful network of information, like creating Google maps from scratch? I certainly can’t, but Eclipse BioInnovations, a San Diego-based biotech start-up, is aiming to do just that for RNA therapeutics.

Researchers at the University of California San Diego, who are also Eclipse co-founders, captured a high-resolution picture of the inner workings of gene regulation. They created the largest maps of the network of RNA binding proteins, the RNA sequences they bind to, and what the proteins do. The better resolution the map, the more researchers understand.

“By identifying where all the RNA binding proteins sit, the floodgates start to open for describing how RNA biology is modulated,” said Gene Yeo, Ph.D., MBA, Professor of Cellular and Molecular Medicine at UC San Diego and co-founder of Eclipse. “From a drug development perspective, we’ve laid out the largest landscape to date of almost 360 RNA binding proteins.” …

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Chelsea Weidman Burke, M.S.

Biochemist turned science journalist. Alzheimer’s, immunology, immunotherapy, genetics, cancer. Follow my publication! https://medium.com/chemically-inquisitive

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