Scientists Have Discovered a Drug That Promote Tooth Regrowth and Fixes Cavities
Soon, dental fillings may be left in the dustbin of history, and all that thanks to a recent discovery of one drug, which is called Tideglusib. The drug was initially developed and trialed to treat Alzheimer’s disease. During the test trials, scientist discovered that it also happens to promote the natural tooth regrowth mechanism. In praxis, this means that teeth itself will repair cavities.
How does It work?
The Tideglusib drug works by stimulating stem cells in the pulp of teeth, which are the source of new dentine. Dentine is the mineralized substance beneath the tooth enamel which gets eaten away by tooth decay.
Teeth can naturally regenerate dentine without assistance, but this happens only under certain circumstances. The pulp should usually be exposed to infection (like tooth decay), or maybe by trauma, to prompt the production of dentine. But, even after that, the tooth will only have the ability to regrow a fragile layer naturally, which is not enough to repair cavities caused by tooth decay. This drug will change this outcome, as it turns off the GSK-3 enzyme, which stops dentine from forming.