Vanillin Is an Organic Chemical Compound Used In Perfumes, Flavorings, Pharmaceuticals and Food

Ben Wood
3 min readJun 7, 2022
Vanillin Market
Vanillin Market

There are three types of vanillin: natural, biosynthesized, and synthetic. Biosynthesized vanillin is derived from clove oil and ferulic acid. It is halal and kosher and adheres to Muslim dietary regulations. Both synthetic and natural vanillin are suitable for vegans and vegetarians. These two types of vanillin are processed by three different methods.

The process to produce synthetic vanillin starts with a reaction involving potassium hydroxide and chloroform. Both compounds contain an aldehyde group, and this reaction is what gives vanillin its vanilla flavor. The product is the synthetic form of vanilla, and is often used to replace natural vanillin in baked goods, ice cream, medicines, and cleaning solutions. While this chemical compound may taste better than natural vanillin, it isn’t as effective as the former.

According to Coherent Market Insights the Vanillin Market Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2022–2028

While Vanillin is not difficult to smell, its odor is somewhat harder to determine. It is highly sensitive to contamination and should never come into contact with iron. Besides being a highly volatile and inert substance, Vanillin can discolor soap. Due to this, it is best not to store it near an iron source, as it can produce an unpleasant odor.

While natural vanillin is produced from wood, there are other sources of vanillin, including lignin. One such source is pyrocatechol. This compound undergoes oxidation reactions to produce vanillin. This chemical is known as iso-Vanillin. In Japan, the flavor industry demands iso-Vanillin, which is a form of Vanillin obtained from lignin. However, this chemical is still considered an unreliable source, and it may be a long way off.

Another source of natural vanillin is ferulic acid, which has been shown to bioconvert ferulic acid into vanillin. It has been suggested that several microorganisms are responsible for the production of this flavor. The process involves activating feruloyl-CoA by an enzyme known as feruloyl-CoA synthase. This enzyme then hydrates the thioester of feruloyl-CoA. Enoyl-CoA hydratase and synthase are responsible for the conversion. Natural vanillin is highly expensive, however, can cost 300 times as much as synthetic vanillin. As it is a natural product, it is used in small quantities in foodstuffs. Chemically synthesized vanillin is considerably cheaper, yet is easy to pollute the environment. Its aroma and flavor is similar to that of natural vanillin. However, there are advantages and disadvantages of both types. These two types are often considered natural vanillin.

Along with being naturally produced, synthetic vanillin is widely used in perfumes, air fresheners, soap, and shampoo. While only a fraction of the vanillin produced is used in food, vanillin is also a useful raw material for drugs. It is the main ingredient in L-dopa, a drug used to treat Parkinson’s disease. Natural vanillin is produced by the tiny Melipone bee in Mexico.

Natural vanillin is extracted from the seeds of the Vanilla planifola orchid. This vine native to Mexico is now grown in tropical regions around the world. Madagascar is the largest producer of natural vanillin. The vanilla plant contains about two-thirds vanillin. Vanillin and ethyl vanillin are the two types of vanillin, though the latter one is slightly more expensive. The main difference between the two vanillin varieties is their chemical structure.

Biosynthetic vanillin is produced using petroleum, however, it is still difficult to produce sufficient amounts. The process requires a high-quality raw material and requires specialized strains. Moreover, the yield is low due to high concentrations of undesirable vanillic acid. This method involves extensive incubation times and requires specialized strains. However, the results of bioconversion have been promising. In any case, it remains unclear whose source is responsible for vanillin.

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