David C. Norris, MDDose escalation belies the therapeutic intent of phase I trialsNot long ago in the Journal of Clinical Oncology, bioethicist Jonathan Kimmelman challenged the doctrine of therapeutic intent in phase I…Apr 23, 2018Apr 23, 2018
David C. Norris, MDDebunking the Scanlan Doctrine — Part 2For some 3 decades now, attorney James P. Scanlan has flogged an elementary intuition that invariably functions to undercut efforts to…Apr 2, 2017Apr 2, 2017
David C. Norris, MDDebunking the Scanlan Doctrine — Part 1Last Fall, I enjoyed an exchange with fellow statisticians, debunking a doctrine promulgated by attorney James P. Scanlan for some 30 years…Mar 6, 2017Mar 6, 2017
David C. Norris, MDBacking out of the dead end Prasad and Cifu have reached on ‘reversal’ — Part 2In Part 1 of this review of Prasad and Cifu’s Ending Medical Reversal, I argued that their formulation (and even their naming) of…Sep 15, 2016Sep 15, 2016
David C. Norris, MDBacking out of the dead end Prasad and Cifu have reached on ‘reversal’ — Part 1In Ending Medical Reversal, authors Vinayak K. Prasad and Adam S. Cifu relate a body of significant and important scholarship, using many…Sep 10, 2016Sep 10, 2016