We can fight against HIV by targeting the CD4 cells
The HIV (human immunodeficiency virus) is a virus that attacks immune system’s cells and can lead to the acquired immunodeficiency syndrome (AIDS). The virus attacks immune cells, T-cells (CD4 cells). These cells helps fight the infections. HIV reduces number of T-cells in the body and make it prone to cancer-related diseases and infections.
“This therapy is specifically designed to clear the body of all HIV viruses, including dormant ones” — professor Sarah Fidler, consultant physician at Imperial College London.
The present antiretroviral therapies are able to target infected with HIV CD4 cells (T-cells). They cannot treat dormant CD4 cells, thereby, the body infected by HIV virus despite therapies reproduce the virus and is incurable.
Newly developed therapy involves 2 stages of treatment: consists of a vaccine to help the body to recognise CD4 cells infected by the HIV virus, drug known as Vorinostat activates the dormant CD4 cells. This process could give the immune system a tools to fight against infected cells.
Currently, scientists working on an experimental new therapy said that the virus is now undetectable in a 44-year old HIV-infected man.
“We will continue with medical tests for the next five years and at the moment we are not recommending stopping Art but in the future, depending on the test results we may explore this.” — professor Sarah Fidler.