A Post About Being Wrong

I haven’t written in a while, mostly due to a much-needed break from this to focus on some abstracts and things I needed to get done. I’ll try to get back into the swing of things.

A while ago I created a post about why I thought ketone supplements may be harmful because they may cause more AGE activity and thus, create more health problems.

I was probably wrong. Turns out that a study I read shortly after that post shows a mechanism that says quite the opposite — Ketones may protect against AGEs. What’s more intriguing is that the protective benefits may be independent of any enzyme or cofactor; indicating that beta-hydroxybutyrate may have this impact independent of other mechanisms. This was also postulated in this article, but didn’t show how or why (unlike the first study I mentioned).

This brings me to the second point of this post. I’ve been wrong, and I’m sure I will be wrong. Over and over and over again. I’m OK with that. I’m only as human as everybody else in the world. It doesn’t change anything.

I know and interact with a lot of people that balk at new information that contradicts their preexisting theories/ideas. This bothers me, especially when it comes from self-identifying scientists. The elucidation of new information is why I love science. If there is new information to be discovered then there will always be old information that needs to be corrected. That will always remain constant.

“Known knowns. Unknown knowns. Known unknowns. Unknown Unknowns.”
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