What exactly is histopathology?

Dr. Alherz Anhar Ali
3 min readNov 5, 2022

Also known as a Pathology or Biopsy Report.

Histopathology is the use of a microscope to examine human tissue for signs of disease, damage, or other abnormalities.

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Pathology is the study of disease, while histology is the study of tissues. Thus, histopathology refers to the study of tissues associated with disease.

A histopathology report describes the tissue examined by the pathologist. It can Recognize characteristics of cancer under a microscope.

A histopathology report may also be referred to as a biopsy report or a pathology report.

This article describes the purpose of histopathology, what is included in a histopathology report, and why a histopathology test may be performed. It also discusses how the results are interpreted.

How Does Histopathology Work?:

Histopathology is performed by a pathologist, a specialist who examines tissue under a microscope. Pathologists examine tissue samples in a laboratory.

Pathologists cut and process tissue into very thin layers known as sections. They then stain it and examine it under a microscope. They can observe and document the details of the tissue using a microscope.

Section Frozen:

For some diseases, a tissue sample can be interpreted quickly using frozen sections (also known as Cryosections) obtained during surgery. Frozen sections are examined in the https://pathology.universeconferences.com/lab immediately to provide a result in about 20 minutes.

This pathology is most commonly used to evaluate tumour margins during surgery so that a surgeon can determine whether more tissue should be removed for complete cancer removal.

The use of frozen sections during surgery is determined by the type of cancer removed as well as other factors.

Cancers of the Lymph and Blood:

Lymph nodes are frequently biopsied to screen for certain types of blood cancer and to detect metastases from solid tumours (such as breast cancer and long cancer). Many types of blood cancer may also necessitate a bone marrow biopsy for a definitive diagnosis. ​

A Histopathology Report’s Components

Histopathology reports on surgical cancer specimens can be difficult to understand.

They could include: 4

· A description of how the involved tissue appears

· A prognosis

· A synoptic report outlining the case’s findings

· Pathologist’s remarks

Histopathology reports can be difficult to comprehend, so it is critical to discuss them with a healthcare provider. Knowing which components will be included in your report may assist you in preparing for your appointment.

Histopathology and Related Test:

Additional pathology techniques may be used by doctors to diagnose cancer. For example, molecular techniques examine proteins, receptors, and genes, which aid in the identification of cancer subtypes. Immunohistochemistry searches for markers on cancer cells to determine the type of cancer a person has, whereas chromosomal studies look at gene differences to develop a prognosis.

Summary:

Histopathology is the examination of tissue for signs of disease. In a lab, pathologists perform histopathology. They examine tissue under a microscope and write up their findings.

Histopathology reports may include tissue descriptions, diagnosis, and prognosis. Pathologists may use other techniques to assess and diagnose cancer in addition to evaluating the shape and structure of cells.

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