SARMs: A Novel Class of Anabolic Supplements that Delivers What It Promises
The last few decades have seen an astonishing amount of interest and effort to develop selective androgen receptor modulators (SARMs).
What makes these novel compounds so interesting?
Preclinical studies have demonstrated the ability of SARMs to increase muscle and bone mass which in turn improve physical function without adversely affecting the prostate, liver and cardiovascular after-effects.
Phase I trials of SARMs in humans have reported modest increments in fat-free mass. Hence, the crucial impulse for SARM development has come from proven anabolic effects of these compounds on the skeletal muscle and bone.

SARMs is a gift that keeps on giving
SARMs hold promise as a new category of anabolic therapies supporting functional abilities that have beneficial clinical indications. These include functional limitations associated with aging and chronic disease, frailty, cancer cachexia, and osteoporosis.
As men and women grow old, they lose skeletal muscle mass, strength and power mostly due to the preferential loss of type 2 muscle fibers. Age-associated loss of muscle mass and strength increases the risk of falls, fractures, mobility limitation, physical disability and poor quality of life.
The dual effects of SARMs in muscle and bone might be particularly advantageous for the treatment of osteoporosis, because an increase in muscle mass and strength might help rebuild bone mass and also reduce the risk of fracture because of a reduced chance of falls.

SARMs hold considerable promise as a new class of function promoting anabolic therapies for a variety of clinical indications, such as frailty, functional limitations associated with aging and chronic illnesses, cancer cachexia, and osteoporosis. Other potential applications for SARMs include hormone-replacement therapy, osteoporosis, muscle wasting, male contraception, BPH and prostate cancer
SARMs’ advantage over anabolic steroids
In general, SARMs are defined as tissue-selective Androgen Receptor ligands which demonstrate the following:
(i) high specificity for androgen receptors, specifically in bones and muscles
(ii) improved oral bioavailability
(iii) a pharmacokinetic profile that allows once-a-day administration and,
(iv) a positive, tissue-selective pharmacological activity. This implies promoting anabolic action in muscle, ligament, tendon and bone tissues while eliminating the undesirable side-effects seen in steroidal supplements (like liver toxicity, cardiovascular accidents and prostate cancer)
Are Anabolic steroids more potent than SARMs?
There is no question about the potency of anabolic steroids when it comes to strength and muscle building. With that said the heavy baggage that steroids bring in to the scenario defeats its purpose.
Yes, you can achieve your ideal physique faster with a steroidal supplement but do you really want to bother facing the more permanent, more serious collateral damage it will leave behind? Namely,
· Severe acne, oily skin and hair
· Hair loss
· Liver disease, such as liver tumors and cysts
· Kidney disease
· Heart disease, such as heart attack and stroke
· Altered mood, irritability, increased aggression, depression or suicidal tendencies
· Alterations in cholesterol and other blood lipids
· High blood pressure
· Gynecomastia (abnormal development of mammary glands in men causing breast enlargement)
· Shrinking of testicles
· Azoospermia (absence of sperm in semen)
· Menstrual irregularities in women
· Infertility
· Excess facial or body hair, deeper voice in women
· Stunted growth and height in teens
· Risk of viral or bacterial infections due to unsterile injections Do you really want to
SARMs is selective in its action and does the job efficiently in a fair amount of time. Needless to say, results will be optimal if your SARMs supplement is paired with the proper diet and consistent fitness routine. Between SARMs and anabolic steroids- with both benefits and side effects factored into the equation- hands down, SARMs is the ideal option.
If SARMs work on androgen receptors, does that mean they’re only for men?
Androgen receptors have a widespread expression in many cells and tissues, in both men and women. Androgen receptors are responsible for a diverse range of biological actions including important roles in the development and maintenance of the reproductive, musculoskeletal, cardiovascular, immune, neural and haemopoietic (formation of blood cells in the bone marrow) systems.
And because SARMs are tissue selective, specifically affecting the bone, ligaments, and muscle tissues, it will not cause any adverse effects on other organs systems. Women, rest assured, will achieve their fitness goals without having to worry about reproductive repercussions or masculinizing effects that exogenous steroidal hormones bring about.
Anyone can have a piece of SARMs
The great thing about SARMs, is that they are target-specific, safe to use, and compatible with a wide range of fitness goals that can vary from one person to the other. Whether you are male or female, a professional athlete or a senior, skin and bones or overweight, in great shape or injured, there’s a right SARMs product to meet your particular health objective.
The beauty of SARMs is they not only facilitate in realizing your ideal physique, they also provide physical vigour, strength and amplify athletic performance. Moreover, scientific researches show that SARMs deliver restorative effects in fighting muscle-wasting diseases, metabolic syndromes, bone health debility, and even cancer without the serious adverse effects of pharmaceutical drugs or anabolic steroids.
Basically, you reap mostly the benefits of something anabolic and healing, minus the side effects. With SARMs, you can have your cake, and eat it too!
