Shortage of milrinone for injection
In the short term, milrinone improves the ability of the heart muscle to contract while relaxing the muscles in the walls of the arteries, and has little effect on the rate the heart beats. These are all good for people with chronic heart failure, although safe use requires a heart monitor and available emergency equipment while the drug is in use. Another feature of milrinone is that it acts via a different mechanism than the other two classes of heart drugs that are given over the long term to improve the heart’s function.
The importance of this drug in helping people with chronic heart failure to survive a short-term worsening of their condition is thus plain, but it is nevertheless in short supply, as reported by The American Society of Health-System Pharmacists.