Shortage of enalaprilat for injection
The American Society of Health-System Pharmacists reports a shortage of enalaprilat for injection. This is the active form of a blood pressure medication named enalapril which is taken by mouth and then converted to enalaprilat in the body. Conversion of enalapril to the active form, enalaprilat, is dependent on its being taken by mouth. Thus it is necessary to use the active form when administering the drug by injection.
The link below is to my March 2012 post on this shortage. I include it to point out that the Bedford, Ohio, plant had voluntarily discontinued production at that point and drug shortages resulting from this event are continuing over two years later. Hopefully the takeover by Hikma Pharmaceuticals will provide a solution.