Cataracts cure: Stem cell to re-grow eye’s lens

Cataracts cure: Scientists using Stem cells to re-grow eye’s living lens

Stem cell can cure cataracts by re-growing eye lens , An advanced method by scientists

Coaxing eye’s stem cells by regeneration of lens, the cataracts can be cured.

Scientists made outstanding breakthrough in optical studies, cure for cataract is possible by patient’s own stem cells by re-growing “living lens” in eye which will restore sight in only three months.

12 infants with congenital cataract by birth operated by surgeons removing their damaged lens and coaxing cells to regenerate, it actually reversed their blindness. This stem cell regenerative therapy worked on infants.

Using this technique countless older people will have eyesight restored by their own cells.

Recently the cataract is being diagnosed by eye doctor, inducing an artificial plastic lens to eyes which sometimes lead to inflammation, infection and night time halo effect in sight. While newborns have greater risks as their eyes are still developing.

This new breakthrough will allow scientists to cured cataract without lengthy process of transplant. Scientists at University of California, San Diego are now started to work on aged-based cataracts formed due to clumps of protein build up over time causes clouding effect in sight.

This new outstanding technique wouldn’t need an artificial plastic lens.

Dr Kang Zhang, Chief of Ophthalmic Genetics and founding director of Institute for Genomic Medicine at UC San Diego School of Medicine says “An ultimate goal of stem cell research turned on the regenerative potential of one’s own stem cells for tissue and organ repair and disease therapy,”

This research introduced new horizons of human capability in medical science which represents how new tissue or organ can be regenerated and disease can be cured and it could be a positive step towards the regenerative therapies by harnessing power of regeneration in our body.

“We believe our unique approach will result paradigm shift in cataract surgery and provide patients safer and better cured option in near future”. Said Dr.Kang Zhag.

Anatomy of human eye

Now a day in England the cataract surgery is most common, annually almost 300,000 cataract operations are being performed on NHS. These surgical procedures are done by removing clouded lens and inserting a new artificial plastic lens, called intraocular lens. This conventional method causes large number of people to suffer with unclear vision and they are compulsive to wear spectacles during reading or driving.

On the other hand this new procedure is done by removal of lens leaving behind lens capsule, a membrane which provides lens its natural shape to function, nearby regenerative stem cells are then moved to the membrane and start to regenerate in transparent and fully operational lens.

Approximately 300 babies with congenital cataract are born in Britain every year. The stem cell transplant performed on 12 babies under the age of two are observed to heal quick and perfectly as compared to group of 25 youngsters who had conventional intraocular lens fitted after three months, a clear and regenerated curved lens have formed in all of trials patients eyes.

laser eye surgery clinic

Dr. Dusko llic, Reader in Stem Cell Science, King’s college London,explains trial as “remarkable accomplishment”.

“It one of finest achievement in field of regenerative medicine yet” he said.

He further describes “Current hypothesis about stem cells in eye possibly promote regeneration of surgically removed lens”.

“The hypothesis became reality as the theory was successful by conducting new surgical experiment in primates and rabbits before operation 12 human babies. It’s science at its best”.

How new technique compares

Traditional cataract treatment

This method is done by inserting an artificial plastic lens into the eye called intraocular lens which often leads to inflammation, infection and night time halo effect in vision.

New cataract treatment with stem cell

This method involves the removal of but leaving behind the lens capsule, a membrane which provides lens its natural shape to function. Nearby regenerative stem cells are then moved to the membrane and start to regenerate in transparent and fully operational lens.

The Deputy Head of School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Professor Graham McGeown said ‘this research will evolve the way of cataract treatment’.

“Scientists introduced an evolved technique reduces the eye-sight damaging risk as compared to traditional method which involves lengthy and destructive surgery by implantation of an artificial plastic lens”.

Regeneration process of eye lens after new technique

In Japan, scientists conduct another optical research at Cardiff University and Osaka University which shows the stem cells can be utilize to regenerate many types of tissues from eye in one go.

“The research proves that several types of human stem cells can take on characteristics of cornea, lens and retina.” Said Professor Andrew Quantock of Cardiff University.

“The scientists demonstrate a type of cell called corneal epithelium, can be further synthesize in lab and transplant it on rabbit’s eye where it worked fine, achieved recovered vision”

“These two researches illustrate remarkable regenerative and therapeutic potential of the stem cells. In near future the regeneration of lens could also be possible in old patients.” Said Prof. Julie Daniels.

The NHS annually performs around 4000 corneal grafts which depend on human organ donation.