French biotech company Valneva VLA, +8.23% begins the first clinical trials of its COVID-19 vaccine candidate in sites across the U.K., the government said on Wednesday.
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The Phase 1 and Phase 2 study will involve 150 volunteers in sites across Bristol, Birmingham, Southampton and Newcastle, to evaluate the safety of the experimental shot, and whether it produced an immune response is healthy adults.
If successful, Valneva 0OB3, +9.26% will carry out a larger study in April 2021, with more than 4,000 volunteers testing two doses of the vaccine in two groups: those aged between 18–65 years and over 65s.
The vaccine candidate could then become available by the fourth quarter of 2021.
“While conducting our first clinical trials, we are already ramping-up our manufacturing capacities and commencing production at full-scale so that we can make the vaccine widely available across the world assuming the vaccine is safe and effective,” said Valneva INRLF, -12.80% Chief Executive Thomas Lingelbach.
The experimental shot is being manufactured at a plant in West Lothian, Scotland.
The U.K. government has ordered 60 million doses of Valneva’s experimental shot, which will be delivered in the second half of 2021, with an option to acquire a further 130 million from 2022–2025.
Valneva’s vaccine is the fifth to enter clinical trials in the U.K., alongside those of drug company AstraZeneca AZN, -1.35% and the University of Oxford, Imperial College London, vaccine-development company Novavax NVAX, +7.52% , and Johnson & Johnson JNJ, +2.47% division Janssen Pharmaceuticals, whose studies are currently ongoing.
The start of Valneva’s trial comes just days after the U.K. rolled out its large-scale vaccination program of the shot developed by U.S. drug company Pfizer PFE, +0.41% and its German partner BioNTech BNTX, +0.58% , after it became the first country in the world to approve it on Dec.…
