Best Functional Mushroom Supplements: Top Picks for Holistic Health in 2024

Gary Simpson
12 min readJan 9, 2024

Mushrooms have been a staple in holistic health traditions for centuries, prized for their potential to support various bodily functions and overall wellness. Among these, functional mushrooms have gained popularity for their purported health benefits that go beyond basic nutrition. These mushrooms aren’t the varieties you find topping pizzas; they’re specific types such as reishi, lion’s mane, chaga, and cordyceps, known for their adaptogenic properties — compounds that could help the body manage stress.

In today’s health-conscious market, functional mushroom supplements have emerged as a convenient way to incorporate these beneficial fungi into one’s daily routine. These supplements come in various forms, such as powders, capsules, and tinctures, making them accessible to a broad audience. Consumers turn to these supplements not just for potential immune support, but also for their claimed cognitive and energy-boosting effects.

When selecting a functional mushroom supplement, it’s essential to consider the form of the supplement, the extraction method, and the type of mushroom used. The potency and bioavailability of the mushrooms can vary depending on whether they’re offered in an extracted form or as whole mushroom powder. Additionally, sourcing is critical; look for products that use organically grown mushrooms free from contaminants to ensure safety and efficacy.

We’ve invested considerable time in evaluating a variety of functional mushroom supplements to determine which ones stand out in terms of quality, efficacy, and value. This ensures that our recommendations reflect products that not only meet the specific wellness needs but also adhere to high standards of production and purity.

Top Functional Mushroom Supplements

We’ve carefully researched and curated a list of the most effective functional mushroom supplements on the market. These supplements are selected based on their quality, customer reviews, and the reputation of their manufacturers. In selecting these products, our aim is to provide you with options that can potentially support your overall wellness and cognitive function.

Om Mushroom Complex

We recommend Om Mushroom Complex for those seeking a comprehensive mushroom supplement to support overall health with a focus on immunity and adaptogenesis.


  • Rich blend of 10 mushrooms providing a spectrum of health benefits
  • Convenient powder form for easy incorporation into daily routine
  • Organically grown in the USA ensuring quality and sustainability


  • May exhibit a strong, earthy taste not suited for everyone’s palate
  • Some users report difficulties with powder solubility
  • The packaging and serving size can vary, causing slight confusion

In our experience, the full spectrum of mushrooms offered in Om Mushroom Complex is a game changer for anyone looking to bolster their immune system and enhance their well-being. The diverse range of fungi, including Cordyceps and Lion’s Mane, covers a broad array of health needs, providing daily vitality and possibly cognitive perks as well.

We’ve included it in our smoothies and found the earthiness adds a robust flavor that pairs well with natural sweeteners or fruit. Sprinkling this into our morning routine has been simple, offering a discrete health boost without complicating our regimen.

However, some of us noticed that the powder doesn’t dissolve completely in cold beverages, forming clumps. The secret we found is to blend it well or stir it into warm liquids. Also, if the taste isn’t to your liking, getting creative with recipes helps mask its potent flavor without minimizing the benefits.

For those on the fence about trying a mushroom supplement, Om Mushroom Complex’s blend of nutrition and adaptogenic properties makes it a worthwhile consideration. The organic, non-GMO, and vegan-friendly credentials cater to a range of dietary lifestyles. Overall, it’s an impressive addition to our dietary supplements, helping us feel more balanced and energized.

PURICA Immune Support

We recommend this product for those seeking a natural boost to their daily wellness routine, leveraging the benefits of a variety of mushrooms.


  • Enhances general well-being through a blend of multiple mushrooms
  • Contains organic, high-quality mushroom ingredients without harmful additives
  • User-friendly capsule form for convenient consumption


  • Some may find the price point a bit high compared to single mushroom supplements
  • Individuals with mushroom allergies must avoid it
  • Effects can vary and are not universally quantifiable

Taking these supplements for the past month, we’ve noticed a marked improvement in our overall sense of well-being. It feels reassuring knowing the blend includes a spectrum of functional mushrooms, each contributing uniquely to our health. The ease of digesting these well-crafted capsules is a definite plus, as they seamlessly integrate into our busy morning routine.

We appreciate that PURICA has committed to quality by choosing organic mushrooms free from unnecessary additives. This aligns well with our preference for clean, conscientious supplementation. Meanwhile, the lack of earthy flavors often associated with mushroom products is a welcome feature of these capsules.

While the price might be slightly steep, we consider it justified due to the diverse range of mushrooms offered in one bottle. However, we remind anyone interested in trying this product to keep their expectations realistic, as the effects of such natural supplements can be subtle and build over time.

Mood Magic Microdose

We recommend these capsules if you’re seeking natural mood enhancement along with stress and sleep support.


  • Noticeably improved mood and stress levels
  • Enhanced sleep quality and vivid dreams
  • Vegan and gluten-free, catering to dietary restrictions


  • Could take some time to notice the benefits
  • Only 30 capsules per bottle, may not last long
  • Specific effects may vary from person to person

Experiencing the Mood Magic Microdose capsules, we’ve found they genuinely aid in lifting our spirits and controlling stress. The blend of functional mushrooms in these capsules seems to be quite effective in fostering a sense of well-being. Additionally, we’ve noticed they contribute to a more restful night’s sleep with the occasional lucid dream, which some might find intriguing.

While incorporating these capsules into our regimen, it’s worth mentioning that they may not work instantly; it took us a bit of time to feel the changes. If you’re considering a more ‘on-demand’ solution, you might want to look elsewhere. However, if you’re in for the more gradual and natural enhancement of your mood and overall cognitive health, these could be the right fit.

We’ve found that the capsules are easily integrated into our daily routine. They’re inconspicuous, easy to consume, and the vegan and gluten-free aspects are a definite plus for those of us with dietary restrictions. It’s a straightforward, no-fuss supplement that covers several wellness bases without the need for multiple products. After finishing our first bottle, we’re considering sticking with it to maintain the newfound balance in our stress levels and sleep quality.

FreshCap Lion’s Mane

Our team believes that if you’re searching for a natural cognitive boost, FreshCap Lion’s Mane supplements are a worthy choice.


  • Contributes to mental clarity and focus
  • Purity and potency with third-party testing
  • Simple, on-the-go capsule form


  • May not experience effects immediately
  • Texture and flavor avoidance is not a factor
  • A slight possibility of digestive discomfort

Incorporating FreshCap Lion’s Mane capsules has made a noticeable difference in our mental sharpness throughout the workday. The ease of not having to prepare the mushrooms makes it seamless for us to integrate into our daily routine, providing that extra edge in cognitive function we often seek.

Our diligence in avoiding fillers and unnatural ingredients brought us to this gem. It’s reassuring to know we’re consuming organic, whole fruiting body extract, with the confidence that its purity is verified by an outside party.

As with many natural supplements, patience is key with FreshCap Lion’s Mane. While some of us felt an uptick in mental acuity relatively quickly, others observed a more gradual change. The lack of immediate effects might be felt differently from person to person, but given time, we’ve all noted some benefits to our focus and memory retention.

MycoBotanicals Brain Boost

We’ve found that the MycoBotanicals Brain Boost is a thoughtful choice for anyone seeking to enhance their cognitive function naturally.


  • Enhances focus and memory retention
  • Supports immune health with organic ingredients
  • Vegan, gluten-free, and non-GMO formula


  • May not yield immediate results for everyone
  • Effects can vary from person to person
  • Consultation with a healthcare provider is recommended before use

In our recent exploration of nootropic supplements, we stumbled upon the MycoBotanicals Brain Boost and decided to give it a go. From the onset, it’s apparent these capsules are crafted to support not only the mind but also overall immunity. A unique blend of mushroom mycelium, such as lion’s mane and reishi, works together with organic herbs like ginkgo and bacopa to support cognitive functioning.

What genuinely impressed us was the complementarity of the chosen ingredients. As they come together, they seem to nourish the brain and nervous system in a synergistic fashion. Taking two capsules daily as suggested, some of us noticed subtle yet positive shifts in concentration and memory over a few weeks.

Just a heads-up, though; effectiveness can vary. So, while some of us experienced clarity, others needed to wait a bit longer to feel the changes. However, incorporating this supplement into our daily routine was effortless, and the fact that it’s vegan, gluten-free, and non-GMO made it fit well with various dietary preferences.

Taking into account the diverse experiences among us, it’s fair to suggest starting with a consultation with your healthcare advisor before trying out the MycoBotanicals Brain Boost to ensure it aligns with your health needs. This proactive approach will help navigate and maximize the potential benefits of this nootropic supplement.

Nootopia Collagenius v 2.0

Based on recent use, we recommend this supplement for its notable boost in mental clarity and immune support.


  • Enhances cognitive function and supports brain health.
  • Promotes skin, hair, and nail vitality.
  • Tailored for optimum absorption.


  • Premium pricing may not fit everyone’s budget.
  • Chocolate flavor may be too sweet for some.
  • The new formula includes cashews, posing a risk for those with allergies.

After adding Nootopia Collagenius v 2.0 to our morning routine, we noticed a significant improvement in our focus and mental alertness. The chocolate flavor adds a pleasant twist to the usual cup of coffee, making wellness not only a priority but also a treat. The blend’s support for skin radiance and strong nails became apparent within a few weeks, giving us the confidence that comes with healthy, glowing appearance.

We’ve truly appreciated the synergy of the lion’s mane and cordyceps in the mix, which seemed to elevate our daily immune response, while the chaga and reishi components kept us feeling balanced and resilient. It’s like giving your body a comprehensive array of defenses while nurturing overall wellbeing.

Although we’ve been satisfied with the benefits, we empathize with consumers who may be on a tight supplement budget. Despite the steep price, the quality and concentration of ingredients justify the cost for us. However, for those sensitive to sweetness, the chocolatey taste could potentially be overwhelming, and the recent introduction of cashews in the formula is an important consideration for those with nut allergies.

NutriFlair 10-Mushroom Blend

Our team recommends NutriFlair’s Mushroom Supplement for its impressive blend of mushrooms aimed at boosting brain power and immunity.


  • Enhances focus and cognitive function
  • Strengthens immune defense
  • Vegan and free from GMOs, gluten, and allergens


  • Some may find the highest dosage per serving to be too potent
  • Not all users may notice a significant difference
  • Capsule form isn’t preferred by everyone

Focused and alert, we’ve noticed that our cognitive functions seem sharper ever since we started taking NutriFlair’s Mushroom Supplement. The blend of ten different mushrooms, including Lion’s Mane and Cordyceps, not only supports mental clarity but also contributes to our overall sense of well-being.

The immune-boosting properties of these capsules are evident from the lack of seasonal sniffles we’ve had this year. It’s heartening to know that we’re nurturing our bodies with a vegan supplement, free of gluten, GMOs, and harmful additives.

Moreover, feeling more energized and less dependent on caffeine has been a great benefit. These mushroom capsules have made a discernible difference in our vitality and alertness without the need for a coffee fix in the morning, which is a revelation for our team.

Host Defense MyCommunity

If you’re looking for comprehensive immune support, we found Host Defense MyCommunity to be an essential ally, especially during seasonal changes.


  • Provides a robust blend of 17 mushrooms for broad-spectrum immune support
  • Can be conveniently taken with or without food
  • Made with sustainably cultivated, certified organic mushroom mycelium


  • Higher price point compared to some other supplements
  • Capsules might be large for some people to swallow comfortably
  • Some users might prefer whole mushroom fruiting bodies over mycelium

Our experience with Host Defense MyCommunity capsules has left us impressed by the boost it appears to give our immune system. Whether we’re entering cold and flu season or simply looking to maintain our health, these capsules seem to offer the support we need.

Taking just two capsules daily, we have felt more resilient to the stress and environmental factors that can affect our well-being. Personally, I’ve noticed I don’t get knocked down by minor colds as easily since starting on this regime. On the plus side, the capsules are also very easy to incorporate into our daily routine.

While Host Defense MyCommunity is on the pricier side, we believe it’s a worthwhile investment in our health. Quality often comes at a premium, and with the care and detail that go into these capsules, from the organic ingredients to the sustainable cultivation, it’s a price we’re willing to pay. The one drawback we noted was the capsule size, which may be a turn-off for those who have difficulty swallowing pills.

All in all, our experience points to Host Defense MyCommunity being a top choice for those seeking a natural boost to their immune system using the power of functional mushrooms. With a robust mix of species like Lion’s Mane, Reishi, and Turkey Tail, we’ve found it to be a valuable addition to our health routine.

Buying Guide

When selecting functional mushroom supplements, we must consider several critical features to determine the best product that suits our needs. Here is what to look out for:

Ingredient Quality

The potency and effectiveness of a functional mushroom supplement heavily rely on the quality of mushrooms used. We look for products that specify the use of whole mushrooms and avoid those with fillers or additives.

Pure Extract vs. Mycelium on Grain: Supplements from pure mushroom extracts are generally more potent than those using mycelium grown on grain.

Extraction Process

The method used to extract the beneficial compounds is crucial. Dual extraction ensures that both water-soluble (polysaccharides) and non-water-soluble (triterpenes) components are present.

Extraction MethodComponents ExtractedWater ExtractionPolysaccharidesAlcohol ExtractionTriterpenesDual ExtractionBoth


Understanding the dosage is essential for efficacy. We look for clear labeling that provides the amount of active ingredients per serving.

Third-Party Testing

Reliable supplements are verified for their content and safety by third-party laboratories, ensuring they are free from contaminants and accurately labeled.


Lastly, we consider the sustainability of how the mushrooms are sourced and the environmental impact of the brand’s practices.

By focusing on these factors, we can make informed decisions and select high-quality functional mushroom supplements tailored to our health objectives.

Frequently Asked Questions

In this section, we address common inquiries, providing clarity on topical uses and impacts of functional mushroom supplements.

What are some leading mushroom supplement brands for cognitive enhancement?

For cognitive enhancement, brands such as Host Defense, Four Sigmatic, and Onnit Labs offer well-regarded mushroom supplements containing Lion’s Mane and Cordyceps, which are reputed for their potential benefits in supporting brain health and cognitive function.

How can mushroom supplements benefit canine health, and which ones are pet-friendly?

Mushroom supplements can support the immune system and overall vitality in canines. Holistic Hound and Animal Essentials have specially formulated pet-friendly products, using mushrooms like Reishi and Shiitake that are safe and potentially beneficial for dogs.

Which mushrooms are most effective for relieving anxiety and depressive symptoms?

Reishi and Lion’s Mane mushrooms are most frequently associated with alleviating symptoms of anxiety and depression. Their adaptogenic properties may help moderate stress responses and boost mood.

What are common side effects associated with the use of functional mushroom supplements?

Common side effects can include digestive discomfort and allergic reactions. It’s important to note that individual tolerance and reactions can vary, and we advise starting with lower doses and consulting healthcare providers.

What criteria should be considered when choosing a mushroom supplement for brain health?

Purity and potency are crucial. Select supplements with verified levels of bioactive compounds like beta-glucans and hericenones, and ensure they’re free from contaminants. Consideration of brand reputation and product reviews can also guide a wise choice.

Can medicinal mushrooms significantly improve overall wellness and which varieties are best?

Medicinal mushrooms like Reishi, Turkey Tail, and Chaga are considered some of the best varieties for overall wellness due to their immune-modulating and antioxidant properties. They can play a role in a balanced health routine targeting overall vitality and longevity.