Folate or folic acid is referred to as vitamin B9, a key cofactor in one-carbon metabolism. Folate is the common terminology used for a group of molecules including folic acid, folinic acid or 5-formyltetrahydrofolate (5-FTHF), 5-methyltetrahydrofolate (5-MTHF) or L-methylfolate, 10-formyl-tetrahydrofolate (10-formyl-THF), 5,10-methylene-THF and unsubstituted tetrahydrofolate (THF). Supplementation of folate is…