What Is a Trigger Shot


IUI medications can come in several different forms including pills, patches, and injections to name a few. This is where a term called the “trigger shot” comes in. Many people may ask what is a “trigger shot” and why would I have to have one? Why is it even called that?

What Is a Trigger Shot?

A “trigger shot” is a shot given in some IUI treatments that is an injection of the Human Chorionic Gonadatropin (HCG) which is a pregnancy hormone produced by the placenta that encourage the production of progesterone. This is usually given to a patient to “trigger” or “spark” ovulation during a cycle of IVF treatment. This trigger shot “triggers” the entire process of releasing mature eggs to allow the woman to ovulate when the sperm meets the egg in hopes of being able to conceive a pregnancy.

What Medications Are Given for Trigger Shots?

“Trigger shots” are injections of the HCG are given through popular IVF medications like Ovidrel. As the follicles are developed enough the doctor determines when HCG hormones can come in to help produce the final mature eggs that are required. This shot can vary in timing based on when the doctor deems the follicles mature enough to release the best quality egg with the highest chances of being fertilized successfully.

What Happens After I Take My “Trigger Shot”?

After the “trigger shot” is given the HCG from within the Ovidrel (or other) shot will make the woman produce a cycle of ovulation. This will occur generally within 36–40 hours after the “trigger shot” is given. This process is not IVF treatment but rather IUI treatment that is simply a shot given to help the woman start the ovulation process of releasing healthy eggs for the better chances of conception.

Where Can I Purchase My “Trigger Shot”?

IVFPrescriptions.com provides “trigger shots” according to your prescription from your doctor or certified IVF clinic. Trigger shot purchase(s) such as Ovidrel can be completed on our website at IVFPrescriptions.com. A dose of Ovidrel runs $78.00 on our website which is a 50–75% discount of what you would find in traditional pharmacies.


Trigger shots are an injection that is part of the IUI process that encourages the woman’s body to ovulate to produce mature eggs. The production of mature eggs boosts the chances a woman has of conception.

IVF Success Story:

Lucy* and David’s* Story:

Lucy* always knew she wanted children, but at age 34 she was past the optimum “window” of the time in life to have children. Lucy* and her husband David* tried for about two years without any success to conceive children. Lucy* decided to visit her South Wales IVF clinic to see what might be going wrong. The clinic quickly pinpointed David’s* lack of sperm mobility as one of the struggles the couple faced after running some test.

David’s* sperm mobility was in fact SO poor that the only chance the couple had to succeed at having children was IVF with ICSI. Two treatment cycles for Lucy* and David* proved unsuccessful. The whole experience was described by Lucy* was “emotionally battering”. Lucy* even remembers sitting at her desk at work thinking how long this could possibly go on and how she was going to do this yet again only to find out nothing worked.

Lucy* kept her IVF treatments personal not telling anyone except her and David’s* parents and a few close work colleagues who had to know because of Lucy* taking extensive time off of work for her treatments. Lucy* still cites how impressed she is with her coworkers’ emotional support over her going through treatments to have children.

Lucy* ended up taking her third IVF cycle which was successful with the pregnancy of twin girls. While the twins were born early Lucy* ended up with two healthy girls Lily* and Anne*. Lucy* was enthralled with her twins, but the early days were trying as they were not 100% positive if Lily* and Anne* would flourish or have problems. It turned out that all was well, but Lucy* cited that as something that made it tough to get close to the girls really early on as she wanted to. Fear of something not working out meant Lucy* never wanted to be too attached.

Looking back both Lucy* and David* cited that they probably did their IVF cycles too close together and that they should have taken some time to recover emotionally in between each cycle; however, they cite their age and desperation to have children before it was “too late” as a reason to not wait. More support is also key. Lucy* cites that they didn’t share their treatment with many people, and in lieu of that went without unnecessary support from other people that also may have made the process easier.

*names were changed to respect the privacy of the people involved.

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