I believe the issue does not necessarily come from the variety, but both from the seed itself, and as you said the way the vegetables are grown (large monoculture vs small pluriculture). Using hybride seeds, which are now the great majority of seeds will affect the amount of water and pesticides you will need to use. Using ancestral seeds, as shown by Pascal Poot in France, allows you to have a great diversity of species (allowing you a greater resilience to weather change) and to considerably reduces the input. In fact Pascal Poot has grown 400 different ancient species of tomatoes, which grow WITHOUT any water nor pesticide, and have better results per plant (up to 25kg per plant). It is needless to say that the nutrient content of the fruits are much higher than those given by hybride seeds from BOTH the organic and conventional agriculture as shown by our National Research Insititute on Agriculture… (GMOs are forbidden in France so I can’t compare to them). His work is now closely observed by various agrologist around the world for the ‘incredible’ results of his methods, it must be said that he is growing tomatoes in the driest region of France with the poorest soil. My point was that food soveriegnty can only go in pair with seed sovereignty and learning to let nature do her work.
Link to learn about Pascal Poot farming