Interpreting 23andme Raw Genome Data with Google Genomics and BigQuery
Mike Kahn
2672

I think it is important to point out that raw data from companies like 23andMe is research quality and not clinical quality. That means that it has not been validated for accuracy the way a clinical genetic has. I have done research that found up to a 40% false positive rate for genetic variants reported in raw data sets, meaning that 40% of the reported variants were not confirmed (patient was negative) when we ran clinical confirmation testing. Take your raw results with a grain of salt and if you find something alarming (like a pathogenic mutation in a disease-associated gene), speak with a qualified health care provider like a genetic counselor so they can arrange for follow-up confirmation testing.

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