Brewing Beer, Innovative Education and CARA

Week Oct. 9–13

This week was relatively relaxed. It started with review of a neuroscience paper on oxytocin and its effects on patients with Huntington’s disease; findings showed a significant correlation between increased concentration of oxytocin and the ability of the patient to recognize emotional changes in facial expressions. I will discuss this topic at the next Advanced Systems Biology class.

Learning Territories with François Taddei (CRI Founder, Director)

Francois is one of the most inspiring teachers I have had the pleasure to talk with. He really asks thoughtful questions that cut through the noise to find a signal. This class in a nut shell, “In March 2017 François Taddei led a report for the French Minister of Education called “Toward a learning planet. Intensify R&D for lifelong education”. This work is the result of several months of interviews and collaboration with the main education stakeholders and also an open debate on a collaborative online platform. The report tackles the issue of the lack of means in the R&D policy on lifelong education and proposes recommendations to build a common strategy and to implement it in the classrooms (learning environment, teachers training, etc.). During these 3 sessions, François Taddei will discuss with you the outcomes of the report related to collaborative R&D in education and impacts on policy making. He will also share with you the last follow-ups of the mission and how he tries to implement some of the recommendations with local institutional actors who are looking for experimentation.” As seen in the AIRE Booklet.

The first class we talked about how to mobilize the quality of intelligence. At first I thought about how there is so much more to learn today than 10–20–30 years ago. How can we possibly catch everything or even everything on one topic? Although this is interesting to think about it is not what we were discussing. Actually the idea was closer to finding a way to know yourself and be able to self-declare a quantifiable learning process. Someone talked about an application called Shaper which is like tinder but for finding a mentor whom you can talk to about your goals and strategies for success.

We also were prompted to ask ourselves what made this unique CRI environment different and good for learning. How can we optimize the learning process for learning to flow? Can it be as simple as highjacking youtube? Can we remove interstudent competition? Can it be augmented? How can we build a learning society at different levels? How can we build digital tools, physical spaces, hackerspaces etc.? How can we do this anywhere at anytime?

We know learning occurs in many different ways:

Vertical (teacher-student-classroom) transmission.

Children can teach each other.

People can teach themselves.

Hierarchal Collective (coach-team works together towards objective).

How can you change your community into a learning community or learning expedition? Can you identify these communities when you see them? Minecraft, schools of alternative learning, helping younger schools, MOOC for teachers. What are they doing that transmits information without imposing organized development?

Excellent dialogue and pedagogical tool called “hundrED” tracks innovative pedagogy across the world. This open tool engages innovators to view-discuss-debate topics of education k-12 worldwide.

Issues of systemic political issues arise within the education system due to a mistrust in the government system. This needs to be changed to have open dialogue and ability to productively discuss the issues of tomorrow. The world of tomorrow will have unique challenges with the increase of populations, technology and the introduction of A.I. How can we frame the question of education. Francois believes the answer is to have an evolving frame of freedom, this is the CRI, which teaches the ability to recognize the freedoms you have, which you like and gives you the ability to analyze your reflexivity to it. In this way we learn not by force but by interest and passion with an eye to what is slowly evolving around us next.

Innovative Education Policy Sophie Pene

This class was intriguing to me because it is the bridge between the world of biology I know and love and the world of social systems I want to learn how to analyze. It is very social science oriented which presents interesting new perspectives for me and also some not so fun challenges. This class summary is, “ Through various and simple techniques of documentary exploration (ie. anthropologically and sociologically based), the students are expected to build a personal toolkit to learn how to approach and describe phenomena in social science. This toolkit and scientific methodology should involve:
- Local and global scale observations;
- Systemic approach (from pedagogy to public policy, from individual perspectives to collective ones, from ideological/political speeches to realities);
- The use of public data for analysis and rigorous argumentation.

At the end of the course, you will have acquired a panorama of national and global education systems and notions on the main controversies in education communities. A special focus will be given to current forecasts regarding the impact of AI on education in order to get out of the usual opinions and fears regarding AI and to assess its relevance at all levels.

Right now we are in groups, I’m part of the open data and statistics, working on, “a collective open documentary file, i.e a collective POC (proof of concept) on the design of a training module with the following subject: “How to learn to work with an artificial intelligence & how to allow that teachers and learners​ ​become​ ​active​ ​actors​ ​of​ ​positive​ ​change?”​ An additional bonus can be awarded if you bring evidence of activities in the pedagogy club, the data sciences club, the virtual reality club or everything that is linked with learning.” As seen in the AIRE booklet.

Game Design (Anne and Morjun)

Game Loops -> objectives -> challenge (feedback) -> reward -> signs –

Happens at all levels : 1) macro-the game 2) middle-level 3) micro- an action

We talked about the basics of understanding the world of games and video games; Game Genres, Types of Players, Game play. We broke into groups and had discussions about the kind of games we wanted to develop with which kinds of pedagogical objectives. We created a document where each person could vote on the projects we liked to be a part. Next class we will the projects to continue and which ones we kill.


Re: 2017.09.13: J. Lafaye & A. Goyaa: Revealing Age-Related Changes of Adult Hippocampal Neurogenesis

by Jessica Talley Sagot — Wednesday, 11 October 2017, 11:43 AM

+ They used model selection theory to calculate AIC values for each scenario to better observe and calculate a reasonable fit for the sample size. This penalizes over complex models and by increasing and decreasing value they are able to observe other functional outcomes which make it a good tool for observing complex cell systems.

+ They corroborate their models with data and double check literature from this field.

+ Clear explanation of how they characterized master equations to effectively integrate population-level and single-cell level data necessary to explain age-related changes in neurogenesis.

- The graphical prints are so small, I had such a hard time reading the axis.

- Even after they focused on explaining Dkk1 KO they still were not able to make many clear assertions about variable contradictions.

- Weak biological interpretations of the depletion rate of NSCs.

The relationship of Dkk1 deletion and the self-renewal of NSCs is still unclear to me.

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