John Rinn, PhD, is an accomplished biochemist working in areas of RNA biology research. In 2017, Dr. John Rinn joined the BioFrontiers Institute at the University of Colorado Boulder as the Leslie Orgel Professor Professor of RNA Science.
Over the course of his career, Dr. Rinn has authored numerous articles and papers, including one on interchromosomal interactions published in the Journal of Cell Biology. Research for the paper, entitled “Interchromosomal Interactions: A Genomic Love Story of Kissing Chromosomes,” explored the ability of chromosomes to make long distance contact with other chromosomes, whereas most existing knowledge involves how chromosomes communicate with themselves.
The paper sourced data from a pair of primary studies highlighting interchromosomal interactions needed for healthy physiological gene expression programs. Specific aspects of interchromosomal engagements ranged from how lncRNAs and three-dimensional gene positioning contribute to genome organization in the nucleus and how live cell imaging, as well as Hi-C and SPRITE techniques, allow biologists better to comprehend the extent of interchromosomal interactions.
The paper, authored by Philipp G. Maass, A. Rasim Barutcu, and John L. Rinn, can be read in full at JCB.RUPress.org.
Related studies can be found here:
Reorganization of inter-chromosomal interactions in the 2q37-deletion syndrome: embo.embopress.org
Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C: cellpress.com
Spatiotemporal allele organization by allele-specific CRISPR live-cell imaging (SNP-CLING): nature.com
Want to read more from John Rinn? Check out Professor John Rinn’s blog
John Rinn Google Scholar
John Rinn Twitter: @noncodarnia
