While we’re waiting for WebAssembly, I strongly recommend using transpiled languages. There are lots of wonderful choices. They even make writing SPAs much less complicated than in JS with Angular, Ember, React, Backbone, etc. Many companies and developers use transpiled languages to great success. (And I’m not talking about CoffeeScript nor TypeScript nor Babel. I’m talking about using real languages like Smalltalk, Python, Clojure, Dart, Haxe and Scala.)
While we’re waiting for WebAssembly, I strongly recommend using transpiled languages.
Richard Kenneth Eng
11

I already use a transpiled language. It’s called ES2015 (or ES6). And you are right, it makes writing SPAs much less complicated. I expect my investment in Javascript and its more advanced dialects thereof to be preserved 100% when/if Web-Assembly comes out. And in that period of time I will be able to recruit from the vast array of developers conversant in that language, rather than looking for a niche Clojure expert.

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