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“COVID toes” are not a sign of SARS-CoV-2 infection (COVID-19) but a result of sedentary lifestyles linked to community lockdown measures, walking around barefoot at home, and a lack of warm footwear — at least according to two small studies published JAMA Dermatology.

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The study from Belgium, led by Dr. Anne Herman, investigated the purplish-red chilblain-like lesions on the feet of 29 patients and the hands of 3 patients of individuals seen at a Brussels dermatology clinic from Apr 10 to 17. They found that COVID-19 is not the cause of these inflammations. For starters, none of the patients tested positive for SARS-CoV-2, the virus that causes COVID-19, or had antibodies against the virus on serologic testing. …


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COVID-19 spreads this way. Thanks for this excellent visual, Marcel Salathe & Nicky Case!

A study published mid-April reported that people infected with SARS-CoV-2, the coronavirus causing COVID-19, might be most contagious during the period before they have symptoms. Two studies published in late May showed that a high percentage of people with COVID-19 could be without symptoms. In one study, Australian researchers reported that 104 of 128 people (81 percent) on a cruise ship who tested positive for the novel coronavirus were asymptomatic. In another study, researchers in Wuhan, China reported that 33 of 78 people (42 percent) who tested positive for COVID-19 were without symptoms.

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Most recently, a multi center study published in Travel Medicine and Infectious Disease shows that 60% of asymptomatic (symptom-free) COVID-19 patients in Sichuan province, China, were diagnosed as having pneumonia on their first computed tomography (CT) scan. The study involved 100 asymptomatic and 411 symptomatic coronavirus patients in hospitals in 21 cities and 47 counties or districts from Jan 25 to Feb 20. The investigators also found that patients without symptoms were younger and came from higher-altitude areas with less resident mobility and more defined epidemiologic history than patients with symptoms but had similar rates of underlying conditions. Of the 100 well-documented asymptomatic cases, 17 (27.4%) later developed symptoms, 2 of the older patients developed severe symptoms during hospitalization. No asymptomatic patients died. One patient was believed to have transmitted the virus during the incubation period. …


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Previous studies have demonstrated that SARS-CoV-2, the virus that causes COVID-19, is stable on surfaces for extended periods under indoor conditions. A research in China demonstrated sustained coronavirus transmission despite changing weather conditions in different parts of the country that ranged from cold and dry to warm and humid. A study in Hong Kong using SARS-CoV-2 in a lab solution showed that increasing temperature decreased the amount of viable virus that could be detected. No infectious virus remained after 30 minutes at 56° Celsius and five minutes at 70°C was enough to inactivate the pathogen.

National Biodefense Analysis and Countermeasures Center

A new study by researchers at the National Biodefense Analysis and Countermeasures Center, a government biodefense research laboratory created by the U.S. Department of Homeland Security, shows that natural sunlight can rapidly inactivate SARS-CoV-2 on surfaces. The findings, which come with caveats, suggest that the potential for fomite transmission may be significantly reduced in outdoor environments exposed to direct sunlight. …

About

Dr. Melvin Sanicas

Physician-Scientist • #GlobalHealth #InfectiousDiseases #DigitalHealth • Writes about innovation, vaccines, pathogens, outbreaks, public health

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