I think there are considerable differences between the Democratic and Republican parties, yes.
There are areas of overlap, of course, but they offer significantly different approaches to:
- climate change, and the associated energy regulations
- healthcare (especially Obamacare)
- financial regulation (one supports the post-crisis regulations that Wall St. has spent millions lobbying against, the other wants to repeal them)
And quite a bit more.
My biggest area of concern is foreign policy, and, while there are areas of overlap there as well, the two parties have approached it quite differently.
For example, Al Gore almost certainly would have invaded Afghanistan after 9/11, but not Iraq. For better or worse, launching the Iraq War was a world-changing decision, and it’s unlikely a Democrat would have done it.