Navigating the Side Effects of Trelegy Ellipta: A Comprehensive Guide

PharmaServe
5 min readJul 27, 2023

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Understanding the potential side effects of any medication is an essential aspect of managing your health effectively. This holds true when it comes to the use of Trelegy Ellipta, a medication often prescribed for people with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. This blog aims to offer a comprehensive guide to navigating the potential side effects of Trelegy Ellipta, helping patients and caregivers make informed decisions about their healthcare.

What is Trelegy Ellipta?

Before diving into the potential side effects, it’s essential to understand what Trelegy Ellipta is and its purpose. Trelegy Ellipta is a combination medication that contains three active ingredients: fluticasone, umeclidinium, and vilanterol. This medication works to reduce inflammation, relax the muscles around the airways, and improve breathing. It is often prescribed when other medications have not sufficiently controlled the symptoms of COPD.

Benefits of Trelegy Ellipta

Trelegy Ellipta is unique in that it combines three effective COPD medications into one convenient inhaler. The key benefits of this medication are:

Efficiency

By having three active ingredients, Trelegy Ellipta works to reduce inflammation, relax airway muscles, and improve lung function. This comprehensive approach can often lead to improved symptom control compared to single or dual therapy.

Convenience

With three medications in one inhaler, patients have fewer inhalers to manage and remember. This can improve medication adherence and, subsequently, the overall effectiveness of treatment.

Improved quality of life

The ultimate goal of Trelegy Ellipta is to enhance the quality of life for people with COPD by reducing symptoms such as shortness of breath and the frequency of COPD flare-ups.

Common Side Effects of Trelegy Ellipta

Like all medications, Trelegy Ellipta may have potential side effects. It’s important to note that not everyone will experience these, as reactions to medications can differ significantly among individuals. Common side effects of Trelegy Ellipta include:

Headache

This is one of the most common side effects reported. Over-the-counter pain medications, rest, and hydration can help alleviate this symptom.

Back pain

Some people may experience discomfort or pain in the back.

Cough

Even though Trelegy Ellipta is used to help with breathing problems, some people may experience a dry cough.

Gastrointestinal issues

Nausea, vomiting, diarrhea, or constipation can occur. Maintaining a balanced diet and staying hydrated can help manage these symptoms.

Throat irritation

Some people may experience a sore or irritated throat after using this inhaler. Drinking water or sucking on a lozenge after using the inhaler may help to soothe the throat.

Serious Side Effects of Trelegy Ellipta

While the side effects listed above are usually manageable, there are also potentially serious side effects of Trelegy Ellipta. These are less common but require immediate medical attention if they occur. They include:

Allergic reactions

Signs of an allergic reaction to this medication include rashes, itching/swelling (especially of the face/tongue/throat), severe dizziness, and trouble breathing.

Signs of pneumonia

Symptoms such as increased breathing difficulty, fever, and coughing up colored mucus could indicate pneumonia, which requires immediate medical intervention.

Changes in vision

This medication may cause a condition known as narrow-angle glaucoma, which can lead to permanent vision loss if not treated promptly.

Cardiovascular issues

Increased heart rate, chest pain, high blood pressure, or palpitations are serious side effects that require urgent medical care.

Navigating the Side Effects of Trelegy Ellipta

Consult your healthcare provider: This is the most important step. If you are experiencing any side effects, especially severe ones, contacting your healthcare provider is crucial. They can provide guidance on how to manage these symptoms and adjust your medication if necessary.

Maintain a symptom journal

Keeping a record of when you take your medication and any side effects you experience can be helpful for both you and your healthcare provider.

Self-Care

Drinking plenty of water, getting enough rest, eating a balanced diet, and taking over-the-counter medication for mild symptoms (only after consulting your healthcare provider) can help manage minor side effects.

Regular check-ups

Regular follow-ups with your healthcare provider can help monitor the effectiveness of the medication and manage potential side effects early.

Remember, the information in this blog is not a substitute for professional medical advice. Always consult your healthcare provider for personalized medical advice. If you experience any side effects, even those not listed, contact your healthcare provider promptly.

Precautions When Using Trelegy Ellipta

While Trelegy Ellipta offers significant benefits, certain precautions should be considered when using this medication:

Asthma-related death

Trelegy Ellipta is not indicated for the relief of acute bronchospasm or for the treatment of asthma. The vilanterol in Trelegy Ellipta may increase the risk of asthma-related death.

Existing medical conditions

Those with pre-existing conditions like heart disease, high blood pressure, seizures, thyroid disease, diabetes, kidney disease, or an enlarged prostate should discuss these with their healthcare provider before starting Trelegy Ellipta.

Other medications

Trelegy Ellipta may interact with other medications, leading to increased side effects or decreased effectiveness. Always discuss all medications, including over-the-counter drugs and supplements, with your healthcare provider.

Pregnancy and breast-feeding

If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your healthcare provider.

Safety Information

As with any medication, safety is paramount. Below is some key safety information to keep in mind when using Trelegy Ellipta:

Proper use

It’s essential to use Trelegy Ellipta exactly as prescribed by your healthcare provider. This includes learning the correct inhalation technique and not taking more than the recommended dose.

Regular monitoring

Regular check-ups with your healthcare provider are important to monitor your progress, manage side effects, and adjust the treatment as necessary.

Emergency care

Be aware of the signs of severe side effects and understand that they require immediate medical attention. These signs may include severe allergic reactions, worsening breathing problems, chest pain, rapid heartbeat, and changes in vision.

Conclusion

In conclusion, understanding the potential side effects of Trelegy Ellipta can empower you to take an active role in your health management. By staying informed and proactive, you can navigate these side effects successfully and focus on the benefits this medication offers for managing COPD symptoms.

While Trelegy Ellipta offers potential benefits for COPD patients, it’s crucial to understand the precautions and safety information associated with its use. A healthcare provider should always be the first point of contact for any concerns or questions related to medication use and its side effects. Remember, medication safety involves being well-informed and proactive in managing your health.

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