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Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research.
Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing — atom by atom — both a new life-saving immunosuppressant drug, and a drug to combat the virus that causes AIDS.
You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall S
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Book ID Asin: B00AK78PTG
Book Title: The Billion-Dollar Molecule: The Quest for the Perfect Drug
Book Author: Barry Werth
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Book Format Name: Kindle
Book Format Price: $14.99
Book Format Name: Audiobook
Book Format Price: $0.00
Book Format Name: Hardcover
Book Format Price: $32.50
Book Format Name: Paperback
Book Format Price: $11.89
Book Format Name: AudioCD
Book Format Price: $29.99
Book Price: $18.28
Book Category: Kindle Store, Kindle eBooks, Business & Money and unknown
Book Rating: 167 ratings
The Billion-Dollar Molecule: The Quest for the Perfect Drug by Barry Werth Book Review
Name: Ravi Madhavan
Rating: 4.0 out of 5 stars
Title: Watch Your Back
Date: Reviewed in the United States 🇺🇸 on March 3, 2010
Review: Barry Werth’s book provides a view of the high business and personal risks involved in developing drugs. $ 100 million and much more are sought after to research and develop a drug that only has a promise and could easily do nothing or even worse cause harm. That’s the business risk and the leaders have to put on a confident front and do whatever or say whatever to make sure the money keeps coming in. On the personal side many extremely bright and confident PhD/MDs battle it out to be the one that makes the discovery or get credit for it. Quite often this battle is in the same company between friends and colleagues who may not in the end remain as such. Much of it reminds you of high school but then again we probably never do leave that stage as much as we like to think.
The constant use of molecule and target names and descriptions can make a difficult read but there is much more soap opera than science. One finishes the book wondering how we have come so far in medicine/pharmaceuticals but I guess the same competitive spirit that can so often get in the way of progress also can make it go further and its tough to know when its more trouble than benefit.
Name: Raptorduck
Rating: 5.0 out of 5 stars
Title: Put this on your list of biotech must reads.
Date: Reviewed in the United States 🇺🇸 on November 14, 2002
Review: I read this book years ago, yet recall most of its details. It tells the tale of Josh Boger who came out of Harvard to start Vertex Pharmaceuticals, taking you in a captivating fashion through every delicate step from inception to maturity of this company in its quest for the big drug score.
Having spent almost 18 years in this industry as a scientist and entrepreneur myself I can testify to its accurate portrayl of what it is like to start a typical therapeutic biotech. This book provides unique incite into the world of start-up biotechs and the risks that come with them. It even manages to scuttle through the many interesting dynamics of biotech personalities where primadonna scientific wiz kids meet bottom line suits with calculators and some hybridize into a combination of the two.
If you are a potential investor, wish to work in this industry, or already do or even a patient wondering why your treatment/cure is not yet on market and want to understand more about the economics of biotechnology and drug discovery and development from the ground up, this is a must read. It will edify you and entertain you at the same time and you will end up rooting for Josh along the way.
Name: UD
Rating: 5.0 out of 5 stars
Title: No time to breathe! What a thrilling story!
Date: Reviewed in the United States 🇺🇸 on November 26, 2008
Review: Barry Werth has revealed it all for the public — the inside story of the making of Vertex, a fledgling pharmaceutical start-up (which has now achieved much-deserved success and glory). Werth goes to the extent of discussing each individual’s feelings and thoughts (anguish) in candid detail. The story is an adrenaline rush; expect to reach for a few extra cups of coffee while reading this book. The main players are from Harvard, Yale, Merck, the best of the best and all workaholics to the extreme. As the story — the rush to the finish-line — unfolds, you realize that Dr. Joshua Boger, is truly a brilliant, gifted man — both a scholarly researcher and a precocious businessman with a fantastic presence of mind. What’s even more breath-taking is that the entire story is true — the toil, the sweat, the despair, the triumph. I enjoyed every minute while reading this book. I enthusiastically recommend this book to anyone who has a degree in the biomedical sciences.
Name: Doo Dah Man
Rating: 1.0 out of 5 stars
Title: The jacket calls it “Barbarians at the Lab” or something like it. A less apt comparison
Date: Reviewed in the United States 🇺🇸 on March 24, 2015
Review: This book is interminable, fanboy writing. The jacket calls it “Barbarians at the Lab” or something like it. A less apt comparison, I cannot imagine. Anyone who has ready Barbarians at the Gate and is expecting a similar view into the world of venture capital, biotech startups and the then-nascent world of biotech will, in my opinion, be very disappointed. Mr. Werth is not a very good writer. He never met an adverb he didn’t like. It’s beyond distracting, and half the time I don’t even know what he is trying to say. There definitely could be an interesting story here, but this is not it. Mr. Werth never gets the reader invested in his characters. I never found myself caring what happened to any of them. He tells you that so-and-so is a genius and then just keeps telling you, rather than demonstrating and showing the reader what his characters do. And when he does try to venture into the science, he either understands it so deeply that he glosses over much of the explanation or his grasp of the science is not nearly deep enough and his explanations jump to conclusions without adequately explaining what he is talking about. Either way, he leaves the reader too far removed from a full understanding of what is going on, which also makes it very hard to care about the scientists or even keep straight which of them is which. Contrast that with the medical and scientific explanations in Emperor of All Maladies in which the science is imminently readable.
I wanted to love this book. But it was a big swing and a miss. I will not be reading his sequel, The Antidote.
Name: Kindle Customer
Rating: 5.0 out of 5 stars
Title: Masters of the Universe.
Date: Reviewed in the United States 🇺🇸 on February 19, 2016
Review: A fantastic book. Extremely well written. I took an unususual interest in this book as at one point in my career I was doing research on plasmids; mapping the circular pieces of DNA that confer resistance to antibiotics for bacteria. The character vignettes in Mr. Werth’s book are extraordinarily well done. The author definitely DOES HIS HOMEWORK on this one. This is a fascinating investigation into the business and characters involved in a pharmaceutical startup; all the characters involved throughout the book are superstars in their respective fields — truly masters of the universe. Werth is Michael Lewis on steroids. Do yourself a favor and take an incredible adventure with The Billion Dollar Molecule.
