One big problem I see with Wire for business use is Wire’s limitations concerning chat histories. When I exchange, for example my old smartphone with a new one, all chat histories are lost. Messaging platforms like Slack or Telegram don’t have this problems as they are cloud-based. Even Apple is working on a combined E2EE and cloud-based solution for iMessage, so that old chats won’t get lost when adding new devices. Wire even doesn’t have any backup mechanism.