Specifically, scientists (and, in my opinion, smart entrepreneurs and product managers) engage in some open-ended exploration of the domain. They don’t just divine their hypotheses and test them.
The discovery funnel (distill, validate, prove, invest) also omits this important activity. Moreover, many modern scientists subscribe to Karl Popper’s falsificationism, whereby the emphasis in formulating hypotheses is ensuring they are falsifiable, and the emphasis in testing them is seeking to falsify them, not seeking “validation” or “proof”.
These distinctions are admittedly semantic and matters of emphasis, but I think they have real, practical consequences on the successes and failures of entrepreneurs and product managers.