The different design problems and trade-offs that come with them are what make products different from each other. If Mars had the same trade-offs on Milky Way as Snickers, they’d be the same candy bar! So it’s clearly a per-product thing.
There are trade-offs at the organizational level, but in that case the organization is the product. For example, you can have more people, but beyond a certain point you need more hierarchy. If you don’t want hierarchy, you have to have less people.