DNA Sequencing techniques explained

Tiffany Souterre
8 min readMar 19, 2018

Let’s explore the different techniques of DNA sequencing, Sanger Sequencing versus Next Generation Sequencing (NGS), and see their pros and cons.

Sanger Sequencing

In the mid 70’s, Sanger developped a technique to sequence DNA, the Sanger Sequencing. With 99.99% accuracy it is nowadays considered the Gold Standard for clinical research. It works as follows:

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Tiffany Souterre

Ph.D. • Data Engineer • Loves ML, cloud computing, astronomy, sci-fi, food, animals, nature, travelling… https://amagash.github.iog