OGA UYI
2 min readJan 18, 2024

how weight loss drugs work

Introduction
A. Brief overview of the obesity epidemic
B. Introduction to weight loss drugs as a potential solution

II. Types of Weight Loss Drugs
A. Appetite suppressants
1. Mechanism of action
2. Examples: phentermine, diethylpropion
B. Fat absorption inhibitors
1. Mechanism of action
2. Examples: orlistat
C. Metabolism boosters
1. Mechanism of action
2. Examples: phentermine/topiramate combination

III. Appetite Suppressants
A. Impact on neurotransmitters
1. Serotonin and norepinephrine modulation
2. Effects on hunger and satiety

IV. Fat Absorption Inhibitors
A. Inhibition of lipase enzymes
1. How orlistat prevents fat absorption
2. Potential side effects and considerations

V. Metabolism Boosters
A. Influence on central nervous system
1. Stimulation of the sympathetic nervous system
2. Combination therapies for enhanced effects

VI. Safety and Side Effects
A. Common side effects across different drug types
B. Long-term considerations and risks
C. Importance of medical supervision

VII. Effectiveness and Limitations

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A. Review of clinical studies and efficacy
B. Individual variations in response
C. Addressing challenges and maintaining weight loss

VIII. Lifestyle Changes Alongside Medication
A. Importance of diet and exercise
B. Behavioral modifications for sustainable results

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IX. Conclusion
A. Recap of key points
B. Consideration of weight loss drugs as part of a comprehensive approach