I use the iControlWP wordpress site management system that uses 2-factor authentication as an login security option (as well as other options) and it takes care of site backups, a whole plethora of other security options, site core, theme and plugin updates. I manage 20 client wordpress sites with it, and it makes that job as close to easy as I can imagine. I’ve not had any plugin conflicts from it. The coders are pro-active in feature development, plus, the customer service is very responsive and thorough (they actually read what you’ve written and respond intelligently!). I highly recommend it for anyone managing WP sites; it has saved my sanity as a website designer.