Introducing Brainance

Imagine if you could apply all the state-of-the-art methodologies for the processing of your brain MRI datasets through your web browser.

Imagine if you needed no more time for software installations and you could access your datasets and the processing results from any device that you used as long as it had an internet connection.

Imagine if you could also share selected datasets with your clinical or research colleagues and work collaboratively for the processing of the medical images while working from different timezones.

Brainance MD teaser video

Advantis has invested a lot of time and research on making all the above available for you on your daily clinical or research practice and we are ready to introduce you to Brainance.

Brainance is a highly sophisticated web-based and user friendly post-processing and 3D visualization software suite, for the processing of three different brain MRI exams: Diffusion, Perfusion and Functional MRI.

Brainance can be used for the analysis and review of any case where Diffusion, Perfusion, Functional MRI or even just anatomical T1 or T2 scans have been acquired as part of the study protocol. Brainance, due to its state-of-the-art algorithms, can be applied in cases of brain tumours where the doctor needs to specify the damage that has been caused in the tumoral and the peritumoral areas. Moreover, other applications regard the cases of TBI, Stroke, Multiple Sclerosis, ALS and other neurodegenerative diseases such as Alzheimer’s.

DTI Module

DTI module

Regarding the DTI processing, several maps (colormap, B0, FA map etc) are automatically calculated, based on the data exported from the MRI unit. The user can then select a region of interest (ROI) and either use the default values of the tracking parameters or modify them, in order to proceed to the tractography step. After conducting the fiber tracking, the user can choose among directional, FA or tract specific color coding for the reconstructed fibers, which can be presented in 2D or 3D space, and exported or saved to PACS. Statistical parameters (fiber length, FA, AD etc.) are also calculated for the reconstructed fiber bundles.

DSC Perfusion

DSC Perfusion module

Regarding the DSC Perfusion processing, the data imported undergo normalisation and leakage correction, following the calculation of Cerebral Blood Volume (CBV, rCBV, nCBV), Cerebral Blood Flow (CBF, rCBF, nCBF), Mean Transit Time (MTT), Time to Peak (TTP), Bolus Start and End time maps. Histogram analysis is also available. Tissue response curves can be viewed for any region of interest (ROI) of the aforementioned maps. Finally, the user has the ability to fuse the perfusion-based calculated maps with the results extracted from the other modules of Brainance.

Functional MRI

fMRI module

Regarding the functional MRI processing, the data exported from the MRI unit pass through several analysis steps in order to gain insight on the experiment-related activations.

Pre-processing steps include slice-time correction, motion correction, coregistration, spatial smoothing, temporal filtering and pre-whitening in order to best prepare the data for the next steps. The statistical analysis to follow is implemented using the general linear model (GLM). The model (design matrix) is automatically set by default, but the user has the opportunity to modify it and then run statistical tests to explore task related activations presence in the voxels.


Brainance MD | fMRI and DTI

Brainance is designed in order to promote the fusion between all the aforementioned MRI modalities. Thus, the user has the ability to combine the results (maps, fiber tracts etc.) of all the aforementioned processing. The most widely used fusion protocol regards the use of the fMRI activated regions as seed ROIs for the reconstruction of their connectivity through fiber tracking in the 3D space.

Advantis has a great focus on user experience, simplicity and usability of developed products. User testing, use of “clean” technology and tested design frameworks such as (Material Design of Google), clear understanding of user needs and approaching the users not only as healthcare professionals but also as users of every-day software applications are the main pillars of developing a friendly and usable software application.

Brainance is designed to scale with your medical image processing needs!

Brainance is a web-application following the SaaS model and the pay as you use scheme. There is no need for installation or maintenance, thus extra costs or hardware limitations are eliminated.

The provided subscription plans can easily apply to any type or size of healthcare organisation that wants to work with an advanced medical imaging tool and provide high quality services to its patients while achieving the best possible return on investment.

Brainance can also be connected with PACSs in order to optimise the data management pipeline.

Learn more about Brainance, at our website and get started by either subscribing online or by scheduling a live demo with our sales team.