Will Cannabis Be Antibiotic of the Future???
The WHO (World Health Organization) recognized antibiotic resistance, when the bacteria no lasting respond to the antibiotics, as the highest warnings to global well-being, food security, & growth that we confront now. Possibly tackling this problem, researchers have presently recognized a compound detected in the cannabis that perhaps able to clear out drug defiant bacteria.
Although the anti-bacterial qualities of CBD had been recognized for some time, till now, clinicians were doubtful on how it could be applied to combat antibiotic resistance. So, to know whether that could be the cause, an association of researchers of McMaster University of Ontario, Canada, selected 5 cannabis composites associated to have antibiotic characteristics.
In selective, they discovered that CBG (Cannabigerol) was especially proficient at counterbalancing the MRSA (Methicillin-Resistant Staphylococcus Aureus), the most prevalent hospital super bugs. Nevertheless, usually liable for mild plagues, as it’s mainly resistant to the antibiotics, it has further been perceived to head to a few fatal conditions.
When analyzed under laboratory circumstances, the researchers inspected how Cannabigerol, not a psycho-active thing, was capable to kill prevalent MRSA bacteria & “persister” cells that’re contrarily resistant to antibiotics & often direct to recur diseases. Besides this, the synthesis was witnessed to also be able of killing “biofilms” (usually quite challenging to be free of) that accumulate on the skin & therapeutic implants.
After examining its effectiveness in the petridish, the researchers selected to examine how it would work in animal specimens. Therefore, they began to apply the mixture to heal diseases in mice. In executing so, they discovered that Cannabigerol was able to heal mice of MRSA viruses as efficiently as the anti-biotic vancomycin, otherwise deemed the last option medication for MRSA viruses.
Although assuring outcomes, the researchers nonetheless suggest that these’re “early days” & the mixture requires to undergo several more experiments, as well as the human tests, ere it may be deemed as a latent treatment substitute for antibiotic-resistant viruses. Especially, Eric Brown, who directed the research said, “There’s more attempt to perform to examine the potential of CBG as the antibiotics from the security viewpoint.”
Unhindered by the ban, the contemporary research stays to rediscover a frequently lengthy list of remedial purposes for marijuana that prove classical folkloric tales scientifically valid. That the natural ganja plant may be the most potent antibiotics accessible on the Globe.
Classical Antibiotic — THC (Marijuana)
Cannabis has been adopted as a remedy for millennia. The antibiotic, antibacterial, analgesic & sedative effects are widely known in African, European, South American, and Ancient Egyptian folk practices to mention just some.
Marijuana was an essential internal & external form and was leading medication for most chronic diseases. Historically, Marijuana has been applied to successfully heal sepsis, gonorrhea, dysentery, and tuberculosis. Even as late as 1843 instances of viruses caused cholera & tetanus, the main executioners of that time were fortunately handled with a raw hemp resin.
Astonishingly, in the entire book of ‘Marijuana as Medicament’, pedagogues Dr. J. Kabalik & Dr. F. Santavy from Palacky University of Czech Republic studied the ancestral application of Marijuana as a medication around the earth. ancestral accounts typically highlight the many healing characteristics of cannabis & don’t state the narcotic influences.
A generally used medication in the west till 1942 when it was excluded from the US pharmacopeia, Marijuana faded unappreciated & demonized till very lately. This efficacious plant is rising from late a publicity kindled smokescreen of misinterpretation & doubt to be applauded once again as initial medication.
What Went Wrong? — Antibiotic Resistance
It has been the case of excess of good quality. Antibiotics, especially the penicillin group are substances applied to annihilate bacteria that create fatal infections in people. Antibiotics aid the immunity in defeating disease.
This’s where the evolutionary journey of the endurance of the healthiest is a mysterious downfall. Some organisms left after the antibiotic therapy are the most immune of the pack & go on to endure & burgeon. Then they grow more immune, more powerful organisms that then need a more intense antibiotic medication. Then, repeatedly, strengthening resistance at each step. Antibiotics grow less efficient as time passes by. An untamed merry-go-round. The circumstance is exacerbated by too much use of antibiotics in daily life.
Antitoxins can be discovered in plenty in cosmetics, animal husbandry, and household items like anti-bacterial surface splashes.
In seventy years after the initial bulk production of penicillin, immune organisms have been readjusting & mutating. The problem first grew its pocked sealed cover circa ’62 in the Vietnam when a kind of the penicillin-resistant gonorrhea arose. Jump ahead to today & there now survives organisms immune to Vancomycin, the most powerful produced antibiotic accessible.
We do not Support or Endorse the Consumption of Ganja/Weed/Marijuana/Cannabis in whatever form. It has been banned in India under the NDPS Act.
Sources
- The Guardian
- World Health Organization
- Cold Spring Harbor Laboratory
- Appendino, Giovanni et al., Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study. J Nat Prod 2008, 71 (8), 1427–1430. https://doi.org/10.1021/np8002673
- Hernández-Cervantes R. et al., Immunoregulatory Role of Cannabinoids during Infectious Disease. Neuroimmunomodulation 2017, 24, 183–199. https://www.karger.com/Article/FullText/481824
- Cabral, G.A. and Griffin-Thomas, L., Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects. Expert Rev Mol Med 2009, 11, e3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768535/
- A New MRSA Defense, MIT Technology Review (2008) https://www.technologyreview.com/s/410815/a-new-mrsa-defense/
