Early-stage companies — Dyno Therapeutics

Axial
Axial
Published in
4 min readAug 20, 2022

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Who leads Dyno?

Dyno Therapeutics was founded by Eric Kelsic, Adrian Veres, Sam Sinai, George Church, and Alan Crane in 2018 to bring machine learning to AAV gene therapies. Eric, Sam, and George had done pioneering work multiplex screening AAV capsids that formed the basis of the company.

What does Dyno do?

Dyno combines machine learning with high-throughput in vivo screening to develop new AAV gene therapies. The company’s platform, CapsidMap, comprehensively maps across the AAV capsid to have different tropism, better packaging, among other features. With this platform, Dyno licenses out the AAV vectors they invent to co-develop with partners.

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