Protein: Comparing the Anabolic Effects of Meat and Plant-Based Sources

Dr. Hussam Hamoush
BeingWell
Published in
4 min readJan 25, 2024
Lol, I love memes

In the world of nutrition, protein is often hailed as the king of macronutrients. It is crucialin muscle building, repair, and overall wellness. However, not all proteins are created equal. A recent study investigated the anabolic effects of meat-based and plant-based proteins in older adults. The findings shed light on the importance of considering protein sources and their impact on muscle protein synthesis rates. This article will delve into the study’s methodology, results, and implications, providing valuable insights for individuals seeking to optimize their protein intake.

The Role of Protein in Muscle Synthesis

Before diving into the study, it’s important to understand the significance of protein in muscle synthesis. Proteins are composed of amino acids, which act as the building blocks for muscle tissue. When we consume protein, our bodies break it down into its constituent amino acids, which are used to repair and build new muscle fibers. This process, known as muscle protein synthesis, is crucial for maintaining and increasing muscle mass.

The Study Design

The study, conducted with a randomized, counter-balanced, cross-over design, involved 16 adults aged 65 to 85. On two separate test days, participants consumed either a whole-food omnivorous meal containing lean ground beef (MEAT) or an isonitrogenous and isocaloric whole-food vegan meal (PLANT). Blood and muscle biopsies were collected over six hours to assess postprandial plasma amino acid profiles and muscle protein synthesis rates.

Amino Acid Absorption: Meat vs. Plant-Based Protein

One of the study’s key findings was the difference in postprandial amino acid absorption between the two meals. MEAT led to higher plasma essential amino acid concentrations compared to PLANT over the 6 hours. This suggests that the protein in meat is more readily absorbed by the body, potentially due to specific amino acids or other factors within the meat matrix.

Muscle Protein Synthesis Rates: Meat vs. Plant-Based Protein

The study also evaluated the impact of protein sources on postprandial muscle protein synthesis rates. The results revealed that ingestion of the whole-food omnivorous meal containing beef (MEAT) resulted in approximately 47% higher muscle protein synthesis rates compared to the vegan meal (PLANT). This difference in anabolic response highlights the importance of considering the complete composition of a meal beyond just the total protein content.

The Whole-Food Matrix: More Than Just Protein

It’s important to note that the presence or absence of various components within the whole-food matrix influences the anabolic response to protein ingestion. In this study, the vegan meal lacked the components found in beef that may have contributed to the higher muscle protein synthesis rates. These components could include specific amino acids, bioactive peptides, or other nutrients that enhance protein digestion and absorption.

Essential Amino Acids: Key Players in Muscle Synthesis

Essential amino acids (EAAs) are essential for muscle protein synthesis as the body cannot synthesize them and must be obtained through diet. The study findings suggest that the meat-based meal (MEAT) provided a more favorable profile of EAAs than the vegan meal (PLANT). This essential amino acid composition differencemay have contributed to the differential anabolic response observed between the two meals.

Implications for Different Populations

The implications of these findings extend beyond older adults participating in the study. The greater anabolic response to the meat-based meal may be particularly relevant for various populations, including those growing, pregnant, nursing, over 40 years old, or recovering from an illness. These individuals may benefit from prioritizing meat or other animal-based protein sources to support optimal muscle protein synthesis and overall health.

Balancing Protein Sources in a Plant-Based Diet

While the study highlights the potential advantages of meat-based protein, it’s important to note that plant-based diets can also provide adequate protein for muscle synthesis. Individuals can ensure they obtain all essential amino acids by incorporating various plant-based protein sources. Combining complementary proteins, such as legumes and grains, can create a complete amino acid profile comparable to animal-based sources.

The Importance of Individual Context

It’s crucial to consider individual context when choosing protein sources. Personal preferences, ethical considerations, and dietary restrictions may influence an individual’s decision to prioritize animal-based or plant-based protein sources. The study’s findings provide valuable insights into the anabolic effects of different protein sources, but the ultimate choice depends on individual goals and values.

Conclusion

In conclusion, the study comparing the anabolic effects of meat-based and plant-based protein highlights the impact of protein sources on muscle protein synthesis rates. The findings suggest that a whole-food omnivorous meal containing beef leads to greater postprandial muscle protein synthesis rates than an isonitrogenous, isocaloric whole-food vegan meal. However, it’s important to remember that plant-based diets can still provide adequate protein for muscle synthesis when various plant-based protein sources are included. Ultimately, the choice of protein source should be based on individual context and goals, considering factors such as personal preferences, ethical considerations, and dietary restrictions.

If you want to see more from this Study, here is the link to direct you to all the findings I used in this article!

https://www.sciencedirect.com/science/article/pii/S0022316623727235?via%3Dihub

--

--

Dr. Hussam Hamoush
BeingWell

Drug store owner and Podcast Host. Stonebriar Pharmacy in Frisco, TX. Part time writer, Full time Advocate.