The Biology of Mindfulness and Mindlessness — A Neuroscientist’s Perspective

Powerful evidence based on the personal experience of a former heroin addict who became a brain scientist

Brian Pennie, PhD
Better Humans
Published in
11 min readJan 21, 2020

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Photo by jesse orrico on Unsplash

I spent most of my life mindlessly obsessing about the past and the future. I was consumed by anxiety and tormented by my mind, but completely unaware of the source of my suffering.

To escape my pain, I used drugs, resulting in 15 years of chronic heroin addiction. Heroin brought me to the very edge, but I was lucky. Pounded into submission by the most painful night of my life, I was forced to look at the world from a completely new perspective.

That was in October 2013, when I was first introduced to mindfulness. Since then, I’ve become an author, a Ph.D. student, and a lecturer at the top two universities in Ireland, all in the area of the neuroscience of mindfulness.

Understanding the science underlying mindfulness and meditation can be a powerful motivation for anyone building these habits. But it’s especially helpful if you’re the kind of person who wants evidence of efficacy before embarking on a new goal. (Gretchin Rubin characterizes this as a personality type of “questioner”.)

How the Brain Works

Neurons

Neurons are the basic building blocks of your brain, and there are about 86 billion of them. A single neuron fires between five and fifty times per second, and on average, each neuron receives five thousand connections from other neurons. So, in the time it takes you to read this sentence, billions of neurons will have fired inside your head — a complex system, to put it mildly.

For every action, thought, and feeling you will ever have, it’s neurons firing that allow you to make sense of the experience. This is the biological basis of learning. The more you practice a certain behaviour — say, mindfulness, or worry — associated neurons become more practised.

These neurons are then required to fire more often and more quickly. To save energy, the brain creates new structures specific to the job at hand. This is the essence of learning, and what we call neuroplasticity.

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Brian Pennie, PhD
Better Humans

Change is possible. I write to show that | Recovered heroin addict turned doctor. www.brianpennie.com